Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[4-(4-cyanophenyl)piperazin-1-yl]-N-(5-hydroxy-2-adamantyl)pyridine-2-carboxamide
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 PubChem ID
SID: 131341792
Canonical SMILES
O[C@@]12CC3CC(C1)[C@H](NC(=O)c1cccc(n1)N1CCN(CC1)c1ccc(cc1)C#N)C(C3)C2
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Compound Formula C27H31N5O2
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 2.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 6.7 nM
   TI
   LI
   LO
   TS