Brief Information of the Compound and Protein
Compound Name
3-[1-(4-chlorophenyl)cyclopropyl]-8-cyclopropyl-[1,2,4]triazolo[4,3-a]pyridine
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PubChem ID
CID: 118709259
Canonical SMILES
Clc1ccc(cc1)C1(CC1)c1nnc2c(cccn12)C1CC1
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Compound Formula C18H16ClN3
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
CL000065 HEK293-EBNA Homo sapiens (Human)  1
1
IC50 = 1.6 nM
   TI
   LI
   LO
   TS