Brief Information of the Compound and Protein
Compound Name
4-[2-(4-methoxy-phenoxy)-2-methyl-propionylamino]-adamantane-1-carboxylic acid amide
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Canonical SMILES
COc1ccc(OC(C)(C)C(=O)N[C@H]2C3CC4CC2C[C@](C(N)=O)(C4)C3)cc1
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Compound Formula C22H30N2O4
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM
2 IC50 = 6.026 nM