Brief Information of the Compound and Protein
Compound Name
2-(2-chloro-4-fluoro-phenoxy)-2-methyl-N-[5-(1H-tetrazol-5-yl)-adamantan-2-yl]-propionamide
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PubChem ID
SID: 16626851
Canonical SMILES
CC(C)(Oc1ccc(F)cc1Cl)C(=O)N[C@H]1C2CC3CC1C[C@](c1nnn[nH]1)(C3)C2
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Compound Formula C21H25ClFN5O2
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10.96 nM
2 IC50 = 11 nM