Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-chloro-5-cyclopropyl-N-propan-2-yl-N-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]benzenesulfonamide
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 PubChem ID
CID: 70688084
Canonical SMILES
CC(C)N(c1ccc(cc1)C(C)(O)C(F)(F)F)S(=O)(=O)c1cc(ccc1Cl)C1CC1
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Compound Formula C21H23ClF3NO3S
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 133 nM
   TI
   LI
   LO
   TS
2
IC50 = 612 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 45 nM