Brief Information of the Compound and Protein
Compound Name
2-[4-(2-cyclopropylphenyl)sulfonylphenyl]-1,1,1-trifluoropropan-2-ol
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PubChem ID
CID: 52943645
Canonical SMILES
CC(O)(c1ccc(cc1)S(=O)(=O)c1ccccc1C1CC1)C(F)(F)F
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Compound Formula C18H17F3O3S
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.2 nM