Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(5-hydroxy-2-adamantyl)-2-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide
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 PubChem ID
SID: 16626936
Canonical SMILES
O[C@@]12CC3CC(C1)[C@H](NC(=O)CN1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(C3)C2
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Compound Formula C22H29F3N4O2
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 8 nM