Brief Information of the Compound and Protein
Compound Name
N-[4-(carbamoylmethyl)cyclohexyl]-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide
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PubChem ID
CID: 15986762
SID: 24266028
Canonical SMILES
C[C@](O)(c1ccc(cc1)C(=O)N(C1CC1)C1CCC(CC(N)=O)CC1)C(F)(F)F
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Compound Formula C21H27F3N2O3
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 315 nM
   TI
   LI
   LO
   TS
2
IC50 = 1190 nM
   TI
   LI
   LO
   TS