Brief Information of the Compound and Protein
Compound Name
(2R)-N-(adamantan-2-yl)-1-(pyridin-2-yl)pyrrolidine-2-carboxamide
    Show/Hide
PubChem ID
CID: 46888868
Canonical SMILES
O=C(NC1C2CC3CC(C2)CC1C3)[C@H]1CCCN1c1ccccn1
    Show/Hide
Compound Formula C20H27N3O
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1 nM