Brief Information of the Compound and Protein
Compound Name
N-[4-chloro-3-[propan-2-yl-[4-(1,1,1-trifluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]phenyl]acetamide
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PubChem ID
CID: 70690113
Canonical SMILES
CC(C)N(c1ccc(cc1)C(C)(O)C(F)(F)F)S(=O)(=O)c1cc(NC(C)=O)ccc1Cl
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Compound Formula C20H22ClF3N2O4S
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 498 nM
   TI
   LI
   LO
   TS
2
IC50 > 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 256 nM