Brief Information of the Compound and Protein
Compound Name
N-(5-hydroxy-2-adamantyl)-2-[(2R)-2-methyl-4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]pyrimidine-4-carboxamide
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PubChem ID
CID: 67466679
Canonical SMILES
C[C@@H]1CN(CCN1c1nccc(n1)C(=O)NC1C2CC3CC1CC(O)(C3)C2)c1ccc(cc1)C(F)(F)F
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Compound Formula C27H32F3N5O2
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 18 nM
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