| Compound ID |
Compound Name |
Compound Formula |
|
CP0576130
|
US10435369, Example 155
Show/Hide
|
C29H29F8NO4S
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0485092
|
4-[[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]amino]-1,1-dioxothian-4-ol
Show/Hide
|
C27H27F8NO5S2
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
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CP0554620
|
N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-2-methyl-2-morpholin-4-ylpropanamide
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|
C30H32F8N2O4S
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
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CP0189843
|
(2S)-N-[(6aS,7R,9aS)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5,6,6a,7,8,9-hexahydrocyclopenta[f]quinolin-7-yl]-2-hydroxy-2-methyl-3-methylsulfonylpropanamide
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|
C26H26F8N2O6S2
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0264827
|
US10435369, Example 164
Show/Hide
|
C27H27F8NO4S
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0343469
|
(2S)-N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-2-hydroxy-2-methyl-3-methylsulfonylpropanamide
Show/Hide
|
C27H27F8NO6S2
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0554622
|
US10435369, Example 205
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|
C25H24F8N2O4S
|
1
|
| 1 |
EC50 = 2.5 nM
|
|
|
|
CP0548370
|
1-((3R,3aS,9bS)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)-3-(2-hydroxy-2-methylpropyl)urea
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|
C27H28F8N2O4S
|
1
|
| 1 |
EC50 = 3.1 nM
|
|
|
|
CP0253979
|
US10435369, Example 137
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|
C26H25F8NO4S
|
2
|
| 1 |
EC50 = 3.6 nM
|
|
|
| 2 |
EC50 = 4 nM
|
|
|
|
CP0537269
|
US10435369, Example 206
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|
C24H22F8N2O3S
|
1
|
| 1 |
EC50 = 3.7 nM
|
|
|
|
CP0352074
|
N-[(6aS,7R,9aS)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5,6,6a,7,8,9-hexahydrocyclopenta[f]quinolin-7-yl]-2-hydroxy-2-methylpropanamide
Show/Hide
|
C25H24F8N2O4S
|
1
|
| 1 |
EC50 = 3.9 nM
|
|
|
|
CP0554621
|
US10435369, Example 185
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|
C26H24F8N2O4S
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
|
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CP0516851
|
N-[4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexyl]methanesulfonamide
Show/Hide
|
C34H35F5N2O6S2
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0136217
|
US10435369, Example 30
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|
C27H27F8NO4S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0512230
|
US11078186, Example 121
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|
C29H31F7N2O4
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0537267
|
(2R,4S)-N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-4-fluoro-5-oxo-1-(trideuteriomethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C28H25F9N2O4S
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0548366
|
N-((3R,3aS,9bS)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)acetamide-2,2,2-d3
Show/Hide
|
C24H21F8NO3S
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0322545
|
(2R)-N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-2-hydroxy-2-methyl-3-methylsulfonylpropanamide
Show/Hide
|
C27H27F8NO6S2
|
1
|
| 1 |
EC50 = 5.5 nM
|
|
|
|
CP0421113
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]piperidine-1-carboxamide
Show/Hide
|
C33H32F5N3O5S
|
1
|
| 1 |
EC50 = 5.6 nM
|
|
|
|
CP0189842
|
N-[(6aS,7R,9aS)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5,6,6a,7,8,9-hexahydrocyclopenta[f]quinolin-7-yl]-3-hydroxy-3-methylbutanamide
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|
C26H26F8N2O4S
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0558396
|
N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-1-methylsulfonylpiperidin-4-amine
Show/Hide
|
C28H30F8N2O4S2
|
1
|
| 1 |
EC50 = 6.7 nM
|
|
|
|
CP0165357
|
4-[(3aR,9bR)-5-ethyl-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3a,4-tetrahydropyrrolo[2,3-c]quinoline-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C30H30F8N2O5S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0202915
|
(1R,4r)-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)cyclohexane-1-carboxylic acid
Show/Hide
|
C29H27F8NO5S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0552898
|
(1R,2S,4R)-4-[(3aR,9bR)-9b-(3-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-2-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0574514
|
(1R,2R,4R)-4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-2-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0558116
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C34H32F5NO6S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0576514
|
2,4-dichloro-3-(4-methoxy-3-propan-2-ylphenoxy)-N-[(4-sulfamoylphenyl)methyl]benzamide
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|
C24H24Cl2N2O5S
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0558397
|
N-((3R,3aS,9bS)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)methanesulfonamide
Show/Hide
|
C23H21F8NO4S2
|
1
|
| 1 |
EC50 = 7.3 nM
|
|
|
|
CP0480091
|
US10435369, Example 131
Show/Hide
|
C28H27F8NO5S
|
1
|
| 1 |
EC50 = 7.4 nM
|
|
|
|
CP0525443
|
[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]-(1,1-dioxothian-4-yl)methanone
Show/Hide
|
C32H30F5NO6S2
|
1
|
| 1 |
EC50 = 7.7 nM
|
|
|
|
CP0088309
|
US10273259, Example 70
Show/Hide
|
C29H27F8NO6S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0352075
|
N-[(6aS,7R,9aS)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5,6,6a,7,8,9-hexahydrocyclopenta[f]quinolin-7-yl]-1,1-dioxothiane-4-carboxamide
Show/Hide
|
C27H26F8N2O5S2
|
1
|
| 1 |
EC50 = 8.4 nM
|
|
|
|
CP0959198
|
(4-(2H-tetrazol-5-yl)cyclohexyl)((3aR,9bR)-7-(2-fluoro-6-(trifluoromethyl)benzyloxy)-9b-(4-fluorophenylsulfonyl)-4,5-dihydro-1H-benzo[e]indol-3(2H,3aH,9bH)-yl)methanone
Show/Hide
|
C34H32F5N5O4S
|
1
|
| 1 |
EC50 = 8.5 nM
|
|
|
|
CP0558395
|
US10435369, Example 133
Show/Hide
|
C24H21F8NO4S
|
1
|
| 1 |
EC50 = 8.5 nM
|
|
|
|
CP0537265
|
US10435369, Example 138
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|
C25H23F8NO4S
|
1
|
| 1 |
EC50 = 8.6 nM
|
|
|
|
CP0352076
|
US10435369, Example 149
Show/Hide
|
C28H27F8NO5S2
|
1
|
| 1 |
EC50 = 8.7 nM
|
|
|
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CP0533855
|
N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-1,1-dioxothian-4-amine
Show/Hide
|
C27H27F8NO4S2
|
1
|
| 1 |
EC50 = 8.7 nM
|
|
|
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CP0088306
|
4-[(3aR,9bR)-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-9b-(4-methylphenyl)sulfonyl-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C30H30F7NO5S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0409605
|
[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]-[(2S,4S)-2-methyl-1,1-dioxothian-4-yl]methanone
Show/Hide
|
C28H27F8NO5S2
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
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CP0558398
|
2-hydroxy-2-methylpropyl ((3R,3aS,9bS)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)carbamate
Show/Hide
|
C27H27F8NO5S
|
1
|
| 1 |
EC50 = 9.1 nM
|
|
|
|
CP0559492
|
[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]-(4-hydroxy-1,1-dioxothian-4-yl)methanone
Show/Hide
|
C32H30F5NO7S2
|
1
|
| 1 |
EC50 = 9.4 nM
|
|
|
|
CP0548368
|
US10435369, Example 148
Show/Hide
|
C24H22F8N2O5S2
|
1
|
| 1 |
EC50 = 9.9 nM
|
|
|
|
CP0075590
|
4-[(3aR,9bR)-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-9b-(3-methylphenyl)sulfonyl-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C30H30F7NO5S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0144851
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-c]quinoline-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C29H28F8N2O5S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0540797
|
(1R,3S,4R)-4-[(3aR,9bR)-9b-(3-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-3-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0558225
|
N-[3,5-dichloro-4-(6-methoxy-5-propan-2-ylpyridin-3-yl)oxyphenyl]-2-(1-methylsulfonylpiperidin-4-yl)acetamide
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|
C23H29Cl2N3O5S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0556809
|
US9458171, 275
Show/Hide
|
C33H30F9N3O5S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
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CP0264828
|
3-[(2S)-2-[(6aR,9aR)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6,6a,8,9-tetrahydro-5H-pyrrolo[2,3-h]isoquinoline-7-carbonyl]-5-oxopyrrolidin-1-yl]propanenitrile
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|
C28H24F8N4O4S
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
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CP0427316
|
2-[(2S)-4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide
Show/Hide
|
C23H23F7N2O5S2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
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CP0202916
|
4-[(3aR,9bR)-9b-(4-chlorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C29H27ClF7NO5S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0071084
|
Bms-986251
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C30H29F8NO5S
|
1
|
| 1 |
EC50 = 12 nM
|
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|
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CP0451302
|
(2R)-N-[(6aS,7R,9aS)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5,6,6a,7,8,9-hexahydrocyclopenta[f]quinolin-7-yl]-2-hydroxy-2-methyl-3-methylsulfonylpropanamide
Show/Hide
|
C26H26F8N2O6S2
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
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CP0129837
|
(1R,3S,4R)-4-[[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]amino]-3-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C29H30F8N2O4S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
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CP0568597
|
(2R,4S)-N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-4-hydroxy-5-oxo-1-(trideuteriomethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C28H26F8N2O5S
|
1
|
| 1 |
EC50 = 12.3 nM
|
|
|
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CP0075511
|
4-[(3aR,9bR)-9b-(3-chlorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C29H27ClF7NO5S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
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CP0134800
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-4-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C35H34F5NO6S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0527118
|
1-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]-2-(1,1-dioxo-1,4-thiazinan-4-yl)ethanone
Show/Hide
|
C32H31F5N2O6S2
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
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CP0394528
|
2-[(2S)-1-(4-fluorophenyl)sulfonyl-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-quinolin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide
Show/Hide
|
C24H25F7N2O5S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
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CP0075588
|
(1S,4s)-4-fluoro-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)cyclohexane-1-carboxylic acid and (1S,4s)-1-fluoro-4-((3aR,9bR)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,3a,4,5,9b-hexahydro-1H-benzo[e]indole-3-carbonyl)cyclohexane-1-carboxylic acid
Show/Hide
|
C29H26F9NO5S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
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CP0421111
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxamide
Show/Hide
|
C34H33F5N2O5S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
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CP0565106
|
ethyl (3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalene-3-carboxylate
Show/Hide
|
C25H22F8O4S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0553176
|
N-[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-(4-methylsulfonylpiperazin-1-yl)acetamide
Show/Hide
|
C23H29Cl2N3O5S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0444769
|
[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-pyrrolo[3,2-f]quinolin-3-yl]-(1,1-dioxothian-4-yl)methanone
Show/Hide
|
C26H24F8N2O5S2
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0533854
|
US10435369, Example 125
Show/Hide
|
C30H30F8N2O4S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0075589
|
US10273259, Example 68
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0075593
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3a,4-tetrahydrochromeno[3,4-b]pyrrole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C28H25F8NO6S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0159794
|
US10273259, Example 13
Show/Hide
|
C29H28F8N2O4S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0311598
|
(3R,5S)-5-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-3-fluoro-1-(2-hydroxy-2-methylpropyl)pyrrolidin-2-one
Show/Hide
|
C30H29F9N2O5S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0075591
|
US10273259, Example 49
Show/Hide
|
C29H28F7NO5S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0088310
|
4-[(3aR,9bR)-9b-(3-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C29H27F8NO5S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0514886
|
US9458171, 344
Show/Hide
|
C34H30F8N4O5S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0517158
|
[(6aR,9aR)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6,6a,8,9-tetrahydro-5H-pyrrolo[2,3-h]isoquinolin-7-yl]-(1,1-dioxothian-4-yl)methanone
Show/Hide
|
C26H24F8N2O5S2
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0574448
|
US10273259, Example 863
Show/Hide
|
C29H25F8N3O4S
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0266947
|
US10273259, Example 66
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
|
CP0144858
|
[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5-methyl-1,2,3a,4-tetrahydropyrrolo[2,3-c]quinolin-3-yl]-(4-hydroxy-1,1-dioxothian-4-yl)methanone
Show/Hide
|
C27H26F8N2O6S2
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0565264
|
(2R,4S)-N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-1-(2-cyanoethyl)-4-hydroxy-5-oxopyrrolidine-2-carboxamide
Show/Hide
|
C30H27F8N3O5S
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0075587
|
US10273259, Example 12
Show/Hide
|
C31H29F8NO5S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0552720
|
US9458171, 24
Show/Hide
|
C34H31F9N2O6S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0159792
|
[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3a,4-tetrahydrochromeno[3,4-b]pyrrol-3-yl]-(4-hydroxy-1,1-dioxothian-4-yl)methanone
Show/Hide
|
C26H23F8NO7S2
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0564752
|
N-[[2,4-dichloro-3-(4-methoxy-3-propan-2-ylphenoxy)phenyl]methyl]-1-sulfamoylazetidine-3-carboxamide
Show/Hide
|
C21H25Cl2N3O5S
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0159796
|
US10273259, Example 69
Show/Hide
|
C27H25F8NO6S2
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0552290
|
US9458171, 171
Show/Hide
|
C35H33F9N2O5S
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0574445
|
3-[(2S)-2-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-pyrrolo[3,2-f]quinoline-3-carbonyl]-5-oxopyrrolidin-1-yl]propanenitrile
Show/Hide
|
C28H24F8N4O4S
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0563473
|
4-[[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]amino]cyclohexane-1-carboxylic acid
Show/Hide
|
C28H28F8N2O4S
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0533852
|
N-((3R,3aS,9bS)-9b-((4-fluorophenyl)sulfonyl)-7-(perfluoropropan-2-yl)-2,3,a3a4,59b-hexahydro-1H-cyclopenta[a]naphthalen-3-yl)-4-hydroxypiperidine-4-carboxamide
Show/Hide
|
C28H28F8N2O4S
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0572050
|
(1,1-dioxothian-4-yl)-[(3R)-3-(4-fluorophenyl)sulfonyl-3-[4-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]phenyl]pyrrolidin-1-yl]methanone
Show/Hide
|
C30H28F5NO6S2
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0427319
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-N-pyridin-4-ylacetamide
Show/Hide
|
C24H18F7N3O4S2
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0165356
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-pyrrolo[2,3-c]quinoline-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C28H26F8N2O5S
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0572775
|
US10435369, Example 197
Show/Hide
|
C26H26F8N2O3S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0427315
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide
Show/Hide
|
C23H23F7N2O5S2
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0136114
|
US9458171, 387
Show/Hide
|
C29H29F8NO5S
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0559525
|
[(3R)-3-[4-[[2-chloro-6-(trifluoromethyl)phenyl]methoxy]phenyl]-3-(4-fluorophenyl)sulfonylpyrrolidin-1-yl]-(1,1-dioxothian-4-yl)methanone
Show/Hide
|
C30H28ClF4NO6S2
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0556947
|
N-[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-pyridin-4-ylacetamide
Show/Hide
|
C23H22Cl2N2O3
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0537036
|
US9458171, 337
Show/Hide
|
C34H30ClF8NO6S
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0556808
|
US9458171, 155
Show/Hide
|
C33H29F9N2O5S
|
1
|
| 1 |
EC50 = 32 nM
|
|
|
|
CP0125809
|
US9458171, 392
Show/Hide
|
C29H27F8NO5S
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0384663
|
US9458171, 485
Show/Hide
|
C25H23F8NO5S2
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0572187
|
N-[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C23H22Cl2N2O3
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0144855
|
US10273259, Example 11
Show/Hide
|
C27H25F8NO5S2
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0564087
|
US9458171, 332
Show/Hide
|
C36H36F7NO6S
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0553126
|
US9458171, 519
Show/Hide
|
C25H22F9NO5S2
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0552772
|
US9458171, 186
Show/Hide
|
C32H28F9NO5S
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0537033
|
US9458171, 160
Show/Hide
|
C34H30F9NO6S
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0558676
|
US9458171, 280
Show/Hide
|
C31H27F9N2O5S
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0389268
|
N—((S)-2-fluoro-3-hydroxy-3-methylbutyl)-2-((S)-1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,2,3,4-tetrahydroquinolin-2-yl)acetamide
Show/Hide
|
C25H26F8N2O5S
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0540542
|
(1R,3R,4R)-4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-3-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0553608
|
US9458171, 151
Show/Hide
|
C33H29F9N2O5S
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0560286
|
N-[2,4-dichloro-3-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-(1-methylsulfonylpiperidin-4-yl)acetamide
Show/Hide
|
C24H30Cl2N2O5S
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0562779
|
N-[[2,4-dichloro-3-(4-methoxy-3-propan-2-ylphenoxy)phenyl]methyl]-4-methylsulfonylbenzamide
Show/Hide
|
C25H25Cl2NO5S
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0255834
|
US11078186, Example 108
Show/Hide
|
C29H25F7N2O4
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0088307
|
4-[(3aR,9bR)-9b-benzylsulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C30H30F7NO5S
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
|
CP0312498
|
US11078186, Example 106
Show/Hide
|
C29H27F7N2O3
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
|
CP0202912
|
[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-pyrrolo[2,3-c]quinolin-3-yl]-(4-hydroxy-1,1-dioxothian-4-yl)methanone
Show/Hide
|
C26H24F8N2O6S2
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0560215
|
US9458171, 318
Show/Hide
|
C35H31F10NO7S
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0537173
|
US9458171, 341
Show/Hide
|
C35H33F8NO7S
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0572755
|
N-[(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalen-3-yl]-2-hydroxy-N,2-dimethylpropanamide
Show/Hide
|
C27H27F8NO4S
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0427340
|
(�) 2-(1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,2,3,4-tetrahydroquinolin-2-yl)-N-(2-hydroxy-2-methylpropyl)acetamide
Show/Hide
|
C24H25F7N2O5S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0553930
|
US9771320, Example 60
Show/Hide
|
C28H22F7NO3S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0427417
|
US9458171, 116
Show/Hide
|
C26H25F8N3O4S
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0553177
|
N-[3,5-dichloro-4-(3-cyano-5-propan-2-ylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C23H19Cl2N3O2
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0572776
|
US10435369, Example 196
Show/Hide
|
C27H28F8N2O3S
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0511898
|
N-(3-amino-3-oxopropyl)-2,4-dichloro-3-(4-methoxy-3-propan-2-ylphenoxy)benzamide
Show/Hide
|
C20H22Cl2N2O4
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0560216
|
US9458171, 169
Show/Hide
|
C34H31F9N2O5S
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0165363
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C29H27F8NO5S
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0436100
|
US9458171, 119
Show/Hide
|
C29H29F8NO5S
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0528412
|
N-[2,4-dichloro-3-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C25H25Cl2NO5S
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0435666
|
US9458171, 12
Show/Hide
|
C26H26F7N3O5S
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0384347
|
4-[(3R)-3-(4-fluorophenyl)sulfonyl-3-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]pyrrolidine-1-carbonyl]-4-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C28H27F8NO5S
|
1
|
| 1 |
EC50 = 56 nM
|
|
|
|
CP0408910
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-1-morpholin-4-ylethanone
Show/Hide
|
C23H21F7N2O5S2
|
1
|
| 1 |
EC50 = 58 nM
|
|
|
|
CP0423170
|
US9458171, 117
Show/Hide
|
C28H27F8NO5S
|
1
|
| 1 |
EC50 = 61 nM
|
|
|
|
CP0486503
|
(3S,4S)-N-[(4-ethylsulfonylphenyl)methyl]-3-(4-fluorophenyl)-4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-methylpyrrolidine-1-carboxamide
Show/Hide
|
C30H29F7N2O4S
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0533853
|
US10435369, Example 200
Show/Hide
|
C30H33F8N3O3S
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0490045
|
US9458171, 417
Show/Hide
|
C28H28F7NO5S
|
1
|
| 1 |
EC50 = 64 nM
|
|
|
|
CP0540110
|
ethyl (3S,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalene-3-carboxylate
Show/Hide
|
C25H22F8O4S
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0352073
|
3-[(2S)-2-[(6aR,9aS)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6,6a,8,9-tetrahydro-5H-pyrrolo[2,3-h]quinoline-7-carbonyl]-5-oxopyrrolidin-1-yl]propanenitrile
Show/Hide
|
C28H24F8N4O4S
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0238145
|
5-[(5R)-5-[[1-[(2-ethoxyphenyl)methyl]-2,3-dihydroindol-5-yl]carbamoyl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-5-oxopentanoic acid
Show/Hide
|
C32H36N4O6
|
1
|
| 1 |
EC50 = 68 nM
|
|
|
|
CP0416630
|
US9458171, 393
Show/Hide
|
C30H31F8NO5S
|
1
|
| 1 |
EC50 = 68 nM
|
|
|
|
CP0559675
|
(1,1-dioxothian-4-yl)-[(3R)-3-(4-fluorophenyl)sulfonyl-3-[4-[[2-(trifluoromethyl)phenyl]methoxy]phenyl]pyrrolidin-1-yl]methanone
Show/Hide
|
C30H29F4NO6S2
|
1
|
| 1 |
EC50 = 68 nM
|
|
|
|
CP0572186
|
N-[3,5-dichloro-4-(6-methoxy-5-propan-2-ylpyridin-3-yl)oxyphenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C22H21Cl2N3O3
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0573123
|
[(6aR,9aS)-9a-(4-fluorophenyl)sulfonyl-3-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-6,6a,8,9-tetrahydro-5H-pyrrolo[2,3-h]quinolin-7-yl]-(1,1-dioxothian-4-yl)methanone
Show/Hide
|
C26H24F8N2O5S2
|
1
|
| 1 |
EC50 = 71 nM
|
|
|
|
CP0440425
|
US9458171, 386
Show/Hide
|
C27H24F9NO5S
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0511992
|
(3S,4S)-N-[(4-cyanophenyl)methyl]-3-(4-fluorophenyl)-4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-3-methylpyrrolidine-1-carboxamide
Show/Hide
|
C29H24F7N3O2
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0537034
|
US9458171, 335
Show/Hide
|
C35H33F8NO6S
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
|
CP0384660
|
US9458171, 382
Show/Hide
|
C28H27F8NO5S
|
1
|
| 1 |
EC50 = 79 nM
|
|
|
|
CP0408981
|
N-[[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]methyl]-3-hydroxy-3-methylbutanamide
Show/Hide
|
C23H23F7N2O5S2
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0384357
|
US9458171, 499
Show/Hide
|
C27H27F8NO5S2
|
1
|
| 1 |
EC50 = 83 nM
|
|
|
|
CP0556810
|
1-[3-[(3R)-3-[4-[2-[(2,6-difluorophenyl)methoxy]-1,1,1,3,3,3-hexafluoropropan-2-yl]phenyl]-3-(4-fluorophenyl)sulfonylpyrrolidine-1-carbonyl]azetidin-1-yl]ethanone
Show/Hide
|
C32H27F9N2O5S
|
1
|
| 1 |
EC50 = 83 nM
|
|
|
|
CP0408907
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-N-(1,3,4-thiadiazol-2-yl)acetamide
Show/Hide
|
C21H15F7N4O4S3
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0427424
|
US9458171, 422
Show/Hide
|
C29H30F7NO5S
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0532250
|
(1R,2S,4S)-4-[(3aR,9bR)-9b-(3-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-2-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 85 nM
|
|
|
|
CP0564091
|
US9458171, 251
Show/Hide
|
C33H29F9N2O6S
|
1
|
| 1 |
EC50 = 85 nM
|
|
|
|
CP0486502
|
US11078186, Example 112
Show/Hide
|
C27H24F7N3O2
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0427423
|
US9458171, 56
Show/Hide
|
C26H27F7N2O6S2
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0408982
|
methyl 2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]acetate
Show/Hide
|
C20H16F7NO5S2
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
|
CP0556816
|
N-[3,5-dichloro-4-(3-methoxy-5-propan-2-ylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C23H22Cl2N2O3
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0574303
|
US11078186, Example 147
Show/Hide
|
C29H28F6N2O2
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0059605
|
N-[2-(4-ethylphenyl)benzotriazol-5-yl]propanamide
Show/Hide
|
C17H18N4O
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0086554
|
N-(4,6-dimethyl-1,3-benzothiazol-2-yl)-3-methylthiophene-2-carboxamide
Show/Hide
|
C15H14N2OS2
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0410393
|
3-methyl-N-(3-phenyl-1,2-oxazol-5-yl)benzamide
Show/Hide
|
C17H14N2O2
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0537032
|
US9771320, Example 62
Show/Hide
|
C28H22F10O4S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0384653
|
US9458171, 494
Show/Hide
|
C26H25F8NO5S2
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0564749
|
US9458171, 297
Show/Hide
|
C33H36F7NO6S
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0427330
|
US9458171, 415
Show/Hide
|
C27H25ClF7NO5S
|
1
|
| 1 |
EC50 = 106 nM
|
|
|
|
CP0559831
|
(1R,2R,4S)-4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]-2-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 106 nM
|
|
|
|
CP0384348
|
4-[(3R)-3-(4-fluorophenyl)sulfonyl-3-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]pyrrolidine-1-carbonyl]-4-(methoxymethyl)cyclohexane-1-carboxylic acid
Show/Hide
|
C29H29F8NO6S
|
1
|
| 1 |
EC50 = 109 nM
|
|
|
|
CP0564088
|
US9458171, 301
Show/Hide
|
C34H38F7NO6S
|
1
|
| 1 |
EC50 = 112 nM
|
|
|
|
CP0408908
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-1-(3-hydroxyazetidin-1-yl)ethanone
Show/Hide
|
C22H19F7N2O5S2
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0202748
|
US9458171, 95
Show/Hide
|
C27H25F8NO5S
|
1
|
| 1 |
EC50 = 119 nM
|
|
|
|
CP0564750
|
US9771320, Example 57
Show/Hide
|
C28H25F7O3S
|
1
|
| 1 |
EC50 = 119 nM
|
|
|
|
CP0514888
|
US9771320, Example 97
Show/Hide
|
C27H21F9O3S
|
1
|
| 1 |
EC50 = 122 nM
|
|
|
|
CP0384659
|
US9458171, 502
Show/Hide
|
C25H23F8NO6S2
|
1
|
| 1 |
EC50 = 123 nM
|
|
|
|
CP0516850
|
(1,1-dioxothian-4-yl)-[3-(4-fluorophenyl)sulfonyl-3-(4-phenylmethoxyphenyl)pyrrolidin-1-yl]methanone
Show/Hide
|
C29H30FNO6S2
|
1
|
| 1 |
EC50 = 123 nM
|
|
|
|
CP0564751
|
N-[3,5-dichloro-4-(3-fluoro-5-propan-2-ylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C22H19Cl2FN2O2
|
1
|
| 1 |
EC50 = 129 nM
|
|
|
|
CP0553179
|
N-[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-(1-methylsulfonylpyrazol-4-yl)acetamide
Show/Hide
|
C22H23Cl2N3O5S
|
1
|
| 1 |
EC50 = 133 nM
|
|
|
|
CP0455535
|
(5R)-6-acetyl-N-[1-[(2-ethoxyphenyl)methyl]-2,3-dihydroindol-5-yl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
Show/Hide
|
C29H32N4O4
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0553928
|
US9771320, Example 58
Show/Hide
|
C27H22F8O3S
|
1
|
| 1 |
EC50 = 141 nM
|
|
|
|
CP0574251
|
US11078186, Example 25
Show/Hide
|
C28H29F7N2O3
|
1
|
| 1 |
EC50 = 143 nM
|
|
|
|
CP0434781
|
US9458171, 504
Show/Hide
|
C26H25F8NO6S2
|
1
|
| 1 |
EC50 = 146 nM
|
|
|
|
CP0427418
|
US9458171, 120
Show/Hide
|
C30H29F8NO5S
|
1
|
| 1 |
EC50 = 149 nM
|
|
|
|
CP0220668
|
US10273259, Example 411
Show/Hide
|
C28H23F8NO5S
|
1
|
| 1 |
EC50 = 150 nM
|
|
|
|
CP0539410
|
US9458171, 506
Show/Hide
|
C26H26F8N2O5S2
|
1
|
| 1 |
EC50 = 161 nM
|
|
|
|
CP0408973
|
1,1,1,3,3,3-hexafluoro-2-[4-(4-fluorophenyl)sulfonyl-2,3-dihydro-1,4-benzothiazin-7-yl]propan-2-ol
Show/Hide
|
C17H12F7NO3S2
|
2
|
| 1 |
EC50 = 165 nM
|
|
|
| 2 |
EC50 > 4000 nM
|
|
|
|
CP0571285
|
2-[4-(4-chlorophenyl)sulfonyl-2,3-dihydro-1,4-benzothiazin-7-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
Show/Hide
|
C17H12ClF6NO3S2
|
1
|
| 1 |
EC50 = 165 nM
|
|
|
|
CP0560214
|
US9771320, Example 59
Show/Hide
|
C27H22ClF7O3S
|
1
|
| 1 |
EC50 = 166 nM
|
|
|
|
CP0427318
|
1,1,1,3,3,3-hexafluoro-2-[1-(4-fluorophenyl)sulfonyl-4-methyl-2,3-dihydroquinoxalin-6-yl]propan-2-ol
Show/Hide
|
C18H15F7N2O3S
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0482426
|
2-[4-[(6-chloropyridin-3-yl)-dihydroxy-lambda4-sulfanyl]-2,3-dihydro-1,4-benzothiazin-7-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
Show/Hide
|
C16H13ClF6N2O3S2
|
1
|
| 1 |
EC50 = 170 nM
|
|
|
|
CP0311953
|
US11078186, Example 122
Show/Hide
|
C28H28F7N3O4
|
1
|
| 1 |
EC50 = 176 nM
|
|
|
|
CP0556811
|
1-(2-(benzyloxy)-1,1,1,3,3,3-hexafluoropropan-2-yl)-4-(1-((4-fluorophenyl)sulfonyl)cyclopentyl)benzene
Show/Hide
|
C27H23F7O3S
|
1
|
| 1 |
EC50 = 179 nM
|
|
|
|
CP0513828
|
1,1,1,3,3,3-hexafluoro-2-[1-(4-fluorophenyl)sulfonyl-4-methyl-3,4-dihydro-2H-quinolin-6-yl]propan-2-ol
Show/Hide
|
C19H16F7NO3S
|
1
|
| 1 |
EC50 = 195 nM
|
|
|
|
CP0384652
|
US9458171, 103
Show/Hide
|
C27H26F8N2O4S
|
1
|
| 1 |
EC50 = 197 nM
|
|
|
|
CP0478422
|
US9458171, 514
Show/Hide
|
C27H27F8NO4S
|
1
|
| 1 |
EC50 = 200 nM
|
|
|
|
CP0384656
|
US9458171, 402
Show/Hide
|
C28H25F8NO6S
|
1
|
| 1 |
EC50 = 202 nM
|
|
|
|
CP0408976
|
1,1,1,3,3,3-hexafluoro-2-[4-(4-fluorophenyl)sulfonyl-2,3-dihydro-1,4-benzoxazin-7-yl]propan-2-ol
Show/Hide
|
C17H12F7NO4S
|
1
|
| 1 |
EC50 = 203 nM
|
|
|
|
CP0565154
|
US11078186, Example 126
Show/Hide
|
C27H29F7N2O4S
|
1
|
| 1 |
EC50 = 208 nM
|
|
|
|
CP0535106
|
N-[3,5-dichloro-4-(4-fluoro-3-propan-2-ylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C22H19Cl2FN2O2
|
1
|
| 1 |
EC50 = 212 nM
|
|
|
|
CP0535107
|
N-[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]-2-phenylacetamide
Show/Hide
|
C24H23Cl2NO3
|
1
|
| 1 |
EC50 = 212 nM
|
|
|
|
CP0521022
|
1-[1-(4-fluorophenyl)sulfonylcyclopentyl]-4-phenylmethoxybenzene
Show/Hide
|
C24H23FO3S
|
1
|
| 1 |
EC50 = 214 nM
|
|
|
|
CP0535853
|
US9458171, 526
Show/Hide
|
C26H25F8NO6S2
|
1
|
| 1 |
EC50 = 216 nM
|
|
|
|
CP0511990
|
US11078186, Example 72
Show/Hide
|
C28H26F6N2O2
|
1
|
| 1 |
EC50 = 216 nM
|
|
|
|
CP0564175
|
US9771320, Example 64
Show/Hide
|
C33H27F7O3S
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0435665
|
US9458171, 11
Show/Hide
|
C27H27F7N2O5S
|
1
|
| 1 |
EC50 = 224 nM
|
|
|
|
CP0494050
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-N-methylacetamide
Show/Hide
|
C20H17F7N2O4S2
|
1
|
| 1 |
EC50 = 225 nM
|
|
|
|
CP0408971
|
2-[4-(benzenesulfonyl)-2,3-dihydro-1,4-benzothiazin-7-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
Show/Hide
|
C17H13F6NO3S2
|
1
|
| 1 |
EC50 = 230 nM
|
|
|
|
CP0423163
|
1,1,1,3,3,3-hexafluoro-2-(4-(1-((4-fluorophenyl)sulfonyl)cyclopentyl)phenyl)propan-2-ol
Show/Hide
|
C20H17F7O3S
|
1
|
| 1 |
EC50 = 232 nM
|
|
|
|
CP0429976
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]acetamide
Show/Hide
|
C19H15F7N2O4S2
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0416632
|
US9458171, 396
Show/Hide
|
C29H29F8NO5S
|
1
|
| 1 |
EC50 = 266 nM
|
|
|
|
CP0482739
|
US9458171, 104
Show/Hide
|
C27H26F8N2O4S
|
1
|
| 1 |
EC50 = 269 nM
|
|
|
|
CP0075592
|
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-5-propyl-1,2,3a,4-tetrahydropyrrolo[2,3-c]quinoline-3-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C31H32F8N2O5S
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0180479
|
6-acetyl-2-methoxy-N-[1-[(2-methoxyphenyl)methyl]-2,3-dihydroindol-5-yl]-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
Show/Hide
|
C28H30N4O4
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0551899
|
1-(2-chloro-1,1,1,3,3,3-hexafluoropropan-2-yl)-4-(1-((4-fluorophenyl)sulfonyl)cyclopentyl)benzene
Show/Hide
|
C20H16ClF7O2S
|
1
|
| 1 |
EC50 = 271 nM
|
|
|
|
CP0565155
|
US11078186, Example 120
Show/Hide
|
C28H29F7N2O4
|
1
|
| 1 |
EC50 = 279 nM
|
|
|
|
CP0408979
|
1,1,1,3,3,3-hexafluoro-2-[1-(4-fluorophenyl)sulfonyl-3,4-dihydro-2H-quinolin-6-yl]propan-2-ol
Show/Hide
|
C18H14F7NO3S
|
1
|
| 1 |
EC50 = 280 nM
|
|
|
|
CP0267585
|
US11078186, Example 125
Show/Hide
|
C27H28F7N3O3
|
1
|
| 1 |
EC50 = 289 nM
|
|
|
|
CP0416604
|
US9458171, 403
Show/Hide
|
C28H25F8NO6S
|
1
|
| 1 |
EC50 = 293 nM
|
|
|
|
CP0556818
|
[3,5-dichloro-4-(4-methoxy-3-propan-2-ylphenoxy)phenyl]methanol
Show/Hide
|
C17H18Cl2O3
|
1
|
| 1 |
EC50 = 332 nM
|
|
|
|
CP0003740
|
N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
Show/Hide
|
C17H12F9NO3S
|
1
|
| 1 |
EC50 = 333 nM
|
|
|
|
CP0570892
|
US9458171, 295
Show/Hide
|
C32H34F7NO6S
|
1
|
| 1 |
EC50 = 335 nM
|
|
|
|
CP0471353
|
US11078186, Example 66
Show/Hide
|
C23H24F6N2O2
|
1
|
| 1 |
EC50 = 342 nM
|
|
|
|
CP0468595
|
US9458171, 50
Show/Hide
|
C25H24F7NO4S
|
1
|
| 1 |
EC50 = 378 nM
|
|
|
|
CP0427339
|
US9458171, 511
Show/Hide
|
C26H24F8N2O5S
|
1
|
| 1 |
EC50 = 383 nM
|
|
|
|
CP0416621
|
US9458171, 397
Show/Hide
|
C28H25F8NO5S
|
1
|
| 1 |
EC50 = 392 nM
|
|
|
|
CP0432788
|
4-[(3R)-3-(benzenesulfonyl)-3-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]pyrrolidine-1-carbonyl]cyclohexane-1-carboxylic acid
Show/Hide
|
C27H26F7NO5S
|
1
|
| 1 |
EC50 = 396 nM
|
|
|
|
CP0532117
|
1-[3-(4-fluorophenyl)sulfonyl-3-(4-phenylmethoxyphenyl)pyrrolidin-1-yl]-2-pyridin-4-ylethanone
Show/Hide
|
C30H27FN2O4S
|
1
|
| 1 |
EC50 = 474 nM
|
|
|
|
CP0511892
|
1-fluoro-4-((1-(4-(1,1,1,3,3,3-hexafluoro-2-phenoxypropan-2-yl)phenyl)cyclopentyl)sulfonyl)benzene
Show/Hide
|
C26H21F7O3S
|
1
|
| 1 |
EC50 = 481 nM
|
|
|
|
CP0537142
|
1-[1-(4-fluorobenzenesulfonyl)cyclopentyl]-4-(heptafluoropropan-2-yl)benzene
Show/Hide
|
C20H16F8O2S
|
1
|
| 1 |
EC50 = 494 nM
|
|
|
|
CP0311844
|
US11078186, Example 119
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|
C29H28F7N3O3
|
1
|
| 1 |
EC50 = 505 nM
|
|
|
|
CP0478420
|
US9458171, 385
Show/Hide
|
C27H24F9NO5S
|
1
|
| 1 |
EC50 = 508 nM
|
|
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|
CP0513895
|
2-[4-[dihydroxy-(4-methoxyphenyl)-lambda4-sulfanyl]-2,3-dihydro-1,4-benzothiazin-7-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
Show/Hide
|
C18H17F6NO4S2
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0577387
|
[3-(4-fluorophenyl)sulfonyl-3-(4-phenylmethoxyphenyl)pyrrolidin-1-yl]-(oxan-4-yl)methanone
Show/Hide
|
C29H30FNO5S
|
1
|
| 1 |
EC50 = 532 nM
|
|
|
|
CP0416603
|
US9458171, 399
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|
C27H23F8NO5S
|
1
|
| 1 |
EC50 = 590 nM
|
|
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|
CP0440424
|
4-[(3R)-3-(4-fluorophenyl)sulfonyl-3-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]pyrrolidine-1-carbonyl]-4-methoxycyclohexane-1-carboxylic acid
Show/Hide
|
C28H27F8NO6S
|
1
|
| 1 |
EC50 = 594 nM
|
|
|
|
CP0458191
|
US9458171, 3
Show/Hide
|
C19H16F7NO3S
|
1
|
| 1 |
EC50 = 595 nM
|
|
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|
CP0408978
|
1,1,1,3,3,3-hexafluoro-2-[1-(4-fluorophenyl)sulfonyl-3,4-dihydro-2H-quinoxalin-6-yl]propan-2-ol
Show/Hide
|
C17H13F7N2O3S
|
1
|
| 1 |
EC50 = 600 nM
|
|
|
|
CP0521023
|
1-[3-(4-fluorophenyl)sulfonyl-3-(4-phenylmethoxyphenyl)pyrrolidin-1-yl]-2-(oxan-4-yl)ethanone
Show/Hide
|
C30H32FNO5S
|
1
|
| 1 |
EC50 = 623 nM
|
|
|
|
CP0427328
|
US9771320, Example 125
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|
C21H22F4O3S
|
1
|
| 1 |
EC50 = 643 nM
|
|
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|
CP0534392
|
US9458171, 97
Show/Hide
|
C28H28F7NO6S
|
1
|
| 1 |
EC50 = 686 nM
|
|
|
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CP0535831
|
US9458171, 517
Show/Hide
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C26H25F8NO4S
|
1
|
| 1 |
EC50 = 749 nM
|
|
|
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CP0511988
|
US11078186, Example 45
Show/Hide
|
C22H21F6NO2
|
1
|
| 1 |
EC50 = 771 nM
|
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CP0384661
|
4-[(3R)-3-(4-fluorophenyl)sulfonyl-3-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]pyrrolidine-1-carbonyl]-4-methylcyclohexane-1-carboxylic acid
Show/Hide
|
C28H27F8NO5S
|
1
|
| 1 |
EC50 = 776 nM
|
|
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CP0427313
|
1,1,1,3,3,3-hexafluoro-2-[1-(4-fluorophenyl)sulfonyl-4,4-dimethyl-2,3-dihydroquinolin-6-yl]propan-2-ol
Show/Hide
|
C20H18F7NO3S
|
1
|
| 1 |
EC50 = 815 nM
|
|
|
|
CP0267583
|
US11078186, Example 144
Show/Hide
|
C28H26F6N2O2
|
1
|
| 1 |
EC50 = 877 nM
|
|
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|
CP0432789
|
1,1,1,3,3,3-hexafluoro-2-(4-(1-((4-fluorophenyl)sulfonyl)cyclopentyl)phenyl)propan-2-amine
Show/Hide
|
C20H18F7NO2S
|
1
|
| 1 |
EC50 = 888 nM
|
|
|
|
CP0560183
|
US11078186, Example 83
Show/Hide
|
C21H21F6NO3S
|
1
|
| 1 |
EC50 = 941 nM
|
|
|
|
CP0435670
|
US9458171, 62
Show/Hide
|
C21H18F7NO5S
|
1
|
| 1 |
EC50 = 1040 nM
|
|
|
|
CP0532320
|
N-[3,5-dichloro-4-(3-propan-2-ylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C22H20Cl2N2O2
|
1
|
| 1 |
EC50 = 1072 nM
|
|
|
|
CP0537035
|
1-[1-(4-fluorobenzenesulfonyl)cyclopentyl]-4-(1,1,1,3,3,3-hexafluoro-2-methoxypropan-2-yl)benzene
Show/Hide
|
C21H19F7O3S
|
1
|
| 1 |
EC50 = 1130 nM
|
|
|
|
CP0576225
|
US11078186, Example 104
Show/Hide
|
C28H25F7N2O2
|
1
|
| 1 |
EC50 = 1130 nM
|
|
|
|
CP0416606
|
US9458171, 411
Show/Hide
|
C28H27F8NO5S
|
1
|
| 1 |
EC50 = 1167 nM
|
|
|
|
CP0513896
|
1,1,1,3,3,3-hexafluoro-2-[4-(2-fluorophenyl)sulfonyl-2,3-dihydro-1,4-benzothiazin-7-yl]propan-2-ol
Show/Hide
|
C17H12F7NO3S2
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0427338
|
US9458171, 71
Show/Hide
|
C22H21F7N2O4S
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0867529
|
US9458171, 401
Show/Hide
|
C27H25F8N5O3S
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0552292
|
US9458171, 294
Show/Hide
|
C31H32F7NO6S
|
1
|
| 1 |
EC50 = 1260 nM
|
|
|
|
CP0571859
|
US11078186, Example 87
Show/Hide
|
C27H23F6NO2
|
1
|
| 1 |
EC50 = 1310 nM
|
|
|
|
CP0432790
|
1,1,1-trifluoro-2-(4-(1-((4-fluorophenyl)sulfonyl)cyclopentyl)phenyl)propan-2-ol Step A: 1-fluoro-4-((4-iodobenzyl)sulfonyl)benzene
Show/Hide
|
C20H20F4O3S
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0572625
|
US9771320, Example 74
Show/Hide
|
C33H27F7O3S
|
1
|
| 1 |
EC50 = 1450 nM
|
|
|
|
CP0440423
|
US9458171, 400
Show/Hide
|
C27H23F8NO5S
|
1
|
| 1 |
EC50 = 1480 nM
|
|
|
|
CP0574250
|
US11078186, Example 56
Show/Hide
|
C23H23F6NO3
|
1
|
| 1 |
EC50 = 1570 nM
|
|
|
|
CP0408975
|
2-[(2R)-4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide
Show/Hide
|
C23H23F7N2O5S2
|
1
|
| 1 |
EC50 = 1640 nM
|
|
|
|
CP0560182
|
US11078186, Example 27
Show/Hide
|
C27H25F6NO
|
1
|
| 1 |
EC50 = 1920 nM
|
|
|
|
CP0361253
|
6-acetyl-2-methoxy-N-[1-[[2-(trifluoromethoxy)phenyl]methyl]-2,3-dihydroindol-5-yl]-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
Show/Hide
|
C28H27F3N4O4
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0560407
|
US11078186, Example 28
Show/Hide
|
C22H22F6N2O2
|
1
|
| 1 |
EC50 = 2030 nM
|
|
|
|
CP0571286
|
1,1,1,3,3,3-hexafluoro-2-[4-(3-fluorophenyl)sulfonyl-2,3-dihydro-1,4-benzothiazin-7-yl]propan-2-ol
Show/Hide
|
C17H12F7NO3S2
|
1
|
| 1 |
EC50 = 2040 nM
|
|
|
|
CP0577695
|
US11078186, Example 129
Show/Hide
|
C28H28F8N2O2
|
1
|
| 1 |
EC50 = 2190 nM
|
|
|
|
CP0468597
|
US9458171, 48
Show/Hide
|
C21H18F7NO4S
|
1
|
| 1 |
EC50 = 2650 nM
|
|
|
|
CP0492378
|
ethyl (3R,3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalene-3-carboxylate
Show/Hide
|
C25H22F8O4S
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0408980
|
2-[4-(4-fluorophenyl)sulfonyl-7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-2-yl]acetic acid
Show/Hide
|
C19H14F7NO5S2
|
1
|
| 1 |
EC50 = 2780 nM
|
|
|
|
CP0565109
|
US10435369, Example 54
Show/Hide
|
C26H25F8NO4S
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0547493
|
ethyl (3S,3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalene-3-carboxylate
Show/Hide
|
C25H22F8O4S
|
1
|
| 1 |
EC50 = 3500 nM
|
|
|
|
CP0427414
|
1-fluoro-4-(1-(4-(1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yl)phenyl)cyclopentylsulfonyl)benzene
Show/Hide
|
C21H19F7O2S
|
1
|
| 1 |
EC50 = 3650 nM
|
|
|
|
CP0575796
|
US11078186, Example 24
Show/Hide
|
C28H25F7N2O3
|
1
|
| 1 |
EC50 = 3870 nM
|
|
|
|
CP0553965
|
US10435369, Example 71
Show/Hide
|
C29H29F8NO4S
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
|
CP0553966
|
US10435369, Example 70
Show/Hide
|
C30H31F8NO4S
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
|
CP0565111
|
US10435369, Example 72
Show/Hide
|
C28H27F8NO4S
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
|
CP0564174
|
1-[[1,1,1,3,3,3-hexafluoro-2-[4-[1-(4-fluorophenyl)sulfonylcyclopentyl]phenyl]propan-2-yl]oxymethyl]-3-phenylbenzene
Show/Hide
|
C33H27F7O3S
|
1
|
| 1 |
EC50 = 4160 nM
|
|
|
|
CP0548402
|
US9458171, 383
Show/Hide
|
C27H24F9NO5S
|
1
|
| 1 |
EC50 = 4177 nM
|
|
|
|
CP0423165
|
US9458171, 79
Show/Hide
|
C26H26F7N3O5S
|
1
|
| 1 |
EC50 = 4200 nM
|
|
|
|
CP0490044
|
US9458171, 100
Show/Hide
|
C27H25F8NO5S
|
1
|
| 1 |
EC50 = 4230 nM
|
|
|
|
CP0361647
|
US9458171, 16
Show/Hide
|
C27H26F7NO6S
|
1
|
| 1 |
EC50 = 4340 nM
|
|
|
|
CP0427332
|
US9458171, 4
Show/Hide
|
C19H16F7NO3S
|
1
|
| 1 |
EC50 = 4500 nM
|
|
|
|
CP0267584
|
US11078186, Example 85
Show/Hide
|
C28H30F6N2O3
|
1
|
| 1 |
EC50 = 4860 nM
|
|
|
|
CP0565108
|
US10435369, Example 60
Show/Hide
|
C26H25F8NO4S
|
1
|
| 1 |
EC50 = 5000 nM
|
|
|
|
CP0497249
|
US10435369, Example 58
Show/Hide
|
C26H25F8NO4S
|
1
|
| 1 |
EC50 = 6000 nM
|
|
|
|
CP0434779
|
US9458171, 404
Show/Hide
|
C27H23F8NO5S
|
1
|
| 1 |
EC50 = 7295 nM
|
|
|
|
CP0394525
|
2-[(2R)-1-(4-fluorophenyl)sulfonyl-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-3,4-dihydro-2H-quinolin-2-yl]-N-(2-hydroxy-2-methylpropyl)acetamide
Show/Hide
|
C24H25F7N2O5S
|
1
|
| 1 |
EC50 = 7500 nM
|
|
|
|
CP0511989
|
1,1,1,3,3,3-hexafluoro-2-[4-[(3S,4S)-4-methyl-4-phenylpyrrolidin-3-yl]phenyl]propan-2-ol
Show/Hide
|
C20H19F6NO
|
1
|
| 1 |
EC50 = 7910 nM
|
|
|
|
CP0238128
|
(5R)-6-acetyl-2-methoxy-N-[4-[(2-methoxyphenyl)methoxy]phenyl]-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
Show/Hide
|
C26H27N3O5
|
1
|
| 1 |
EC50 = 8100 nM
|
|
|
|
CP0497248
|
US10435369, Example 62
Show/Hide
|
C25H23F8NO4S
|
1
|
| 1 |
EC50 = 9000 nM
|
|
|
|
CP0540113
|
US10435369, Example 73
Show/Hide
|
C27H25F8NO4S
|
1
|
| 1 |
EC50 = 9000 nM
|
|
|
|
CP0555859
|
US10435369, Example 68
Show/Hide
|
C28H25F10NO3S
|
1
|
| 1 |
EC50 = 9000 nM
|
|
|
|
CP0408972
|
1,1,1,3,3,3-hexafluoro-2-[4-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzothiazin-7-yl]propan-2-ol
Show/Hide
|
C18H14F7NOS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0513897
|
(4-fluorophenyl)-[7-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2,3-dihydro-1,4-benzothiazin-4-yl]methanone
Show/Hide
|
C18H12F7NO2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0562612
|
2-[4-[dihydroxy(pyridin-3-yl)-lambda4-sulfanyl]-2,3-dihydro-1,4-benzothiazin-7-yl]-1,1,1,3,3,3-hexafluoropropan-2-ol
Show/Hide
|
C16H14F6N2O3S2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0565110
|
US10435369, Example 57
Show/Hide
|
C26H22F11NO4S
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0537174
|
US9771320, Example 48
Show/Hide
|
C23H21F7O3S
|
1
|
| 1 |
EC50 = 11300 nM
|
|
|
|
CP0555860
|
US10435369, Example 52
Show/Hide
|
C26H25F8NO4S
|
1
|
| 1 |
EC50 = 12000 nM
|
|
|
|
CP0566264
|
US10435369, Example 35
Show/Hide
|
C27H23F10NO3S
|
1
|
| 1 |
EC50 = 13000 nM
|
|
|
|
CP0965105
|
(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-N-(trideuteriomethyl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalene-3-carboxamide
Show/Hide
|
C24H21F8NO3S
|
1
|
| 1 |
EC50 = 13000 nM
|
|
|
|
CP0528411
|
N-[3,5-dichloro-4-(4-methoxy-3-methylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C21H18Cl2N2O3
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0553178
|
N-[3-chloro-4-(2-methyl-5-propan-2-ylphenoxy)phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C23H23ClN2O2
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0540112
|
US10435369, Example 49
Show/Hide
|
C26H21F10NO3S
|
1
|
| 1 |
EC50 = 23000 nM
|
|
|
|
CP0248636
|
6-acetyl-2-methoxy-N-(4-phenylmethoxyphenyl)-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
Show/Hide
|
C25H25N3O4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0253241
|
6-acetyl-N-[4-[(2-chlorophenyl)methoxy]phenyl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
Show/Hide
|
C25H24ClN3O4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0361254
|
(5S)-6-acetyl-2-methoxy-N-[4-[(2-methoxyphenyl)methoxy]phenyl]-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
Show/Hide
|
C26H27N3O5
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0944627
|
(3R,3aS,9bS)-9b-(4-fluorophenyl)sulfonyl-7-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-N,N-bis(trideuteriomethyl)-1,2,3,3a,4,5-hexahydrocyclopenta[a]naphthalene-3-carboxamide
Show/Hide
|
C25H23F8NO3S
|
1
|
| 1 |
EC50 = 33000 nM
|
|
|
|
CP0497247
|
US10435369, Example 41
Show/Hide
|
C27H25F8NO4S
|
1
|
| 1 |
EC50 = 34000 nM
|
|
|
|
CP0540111
|
US10435369, Example 4
Show/Hide
|
C27H25F8NO4S
|
1
|
| 1 |
EC50 = 34000 nM
|
|
|
|
CP0574223
|
US9771320, Example 49
Show/Hide
|
C23H23F7O4S
|
1
|
| 1 |
EC50 > 40000 nM
|
|
|
|
CP0547717
|
US10435369, Example 24
Show/Hide
|
C27H25F8NO4S
|
1
|
| 1 |
EC50 = 47000 nM
|
|
|
|
CP0570335
|
US10435369, Example 67
Show/Hide
|
C29H31F8NO4S
|
1
|
| 1 |
EC50 = 73000 nM
|
|
|
|
CP0560822
|
US10435369, Example 26
Show/Hide
|
C23H19F8NO3S
|
1
|
| 1 |
EC50 = 82000 nM
|
|
|
|
CP0534584
|
(perfluoropropan-2-yl)-2,3,3a,5,9b-hexahydro-1H-cyclopenta[a]naphthalene-3-carboxamide hydrochloride
Show/Hide
|
C27H26F8N2O3S
|
1
|
| 1 |
EC50 = 100000 nM
|
|
|
|
CP0341565
|
N-(3-chloro-4-cyanophenyl)-N'-[3-(cyclopropylmethyl)-1-ethyl-2,4-dioxoquinazolin-6-yl]-3-methylpentanediamide
Show/Hide
|
C27H28ClN5O4
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0904554
|
cis-3-({(5R)-5-[(7-Fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5H)-yl}carbonyl)cyclobutyl]acetic Acid
Show/Hide
|
C28H32FN3O5
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0144908
|
(1R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-6-methoxy-2-(3-oxo-1,2-oxazole-5-carbonyl)-3,4-dihydro-1H-isoquinoline-1-carboxamide
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C24H25F2N3O5Si
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1
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| 1 |
IC50 = 6.1 nM
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CP0144906
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(1R)-2-(5-amino-5-oxopentanoyl)-N-(3,5-difluoro-4-trimethylsilylphenyl)-6-methoxy-3,4-dihydro-1H-isoquinoline-1-carboxamide
Show/Hide
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C25H31F2N3O4Si
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1
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| 1 |
IC50 = 6.7 nM
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CP0560136
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N-[1,3-bis(cyclopropylmethyl)-2,4-dioxoquinazolin-6-yl]-N'-(3-chloro-4-cyanophenyl)-3-methylpentanediamide
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C29H30ClN5O4
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1
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| 1 |
IC50 = 7.2 nM
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CP0053566
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N-[5-(2-chlorobenzoyl)-4-(3-chlorophenyl)-1,3-thiazol-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
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C26H20Cl2N2O4S2
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1
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| 1 |
IC50 = 10 nM
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CP0252170
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N-[(1R)-2-(3,5-difluoro-4-trimethylsilylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-3-oxo-1,2-oxazole-5-carboxamide
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C23H25F2N3O5Si
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1
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| 1 |
IC50 = 13 nM
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CP0904662
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(trans-3-(((5R)-5-((7-Fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl)-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)carbonyl)cyclobutyl)acetic Acid
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C28H32FN3O5
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1
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| 1 |
IC50 = 14 nM
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CP0963908
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5-((1R)-1-((3,5-Difluoro-4-(trimethylsilyl)phenyl)carbamoyl)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-5-oxopentanoic Acid
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C24H29F2N3O5Si
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1
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| 1 |
IC50 = 17 nM
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CP0445966
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N-[2-(3,5-difluoro-4-trimethylsilylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-3-oxo-1,2-oxazole-5-carboxamide
Show/Hide
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C23H25F2N3O5Si
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1
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| 1 |
IC50 = 17 nM
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CP0127326
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5-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-3-methyl-5-oxopentanoic acid
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C26H32F2N2O5Si
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1
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| 1 |
IC50 = 19 nM
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CP0579634
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N-(2-methyl-6-morpholin-4-ylpyridin-3-yl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
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C28H37N3O6S
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1
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| 1 |
IC50 = 19 nM
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CP0867936
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(R)-N-(4-tert-butyl-3-fluorophenyl)-2-(2-(3-hydroxyisoxazol-5-yl)acetyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxamide
Show/Hide
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C26H28FN3O5
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1
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| 1 |
IC50 = 20 nM
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CP0271206
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5-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-5-oxopentanoic acid
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C25H30F2N2O5Si
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1
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| 1 |
IC50 = 23 nM
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CP0549025
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6-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-6-oxohexanoic acid
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C26H32F2N2O5Si
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1
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| 1 |
IC50 = 24 nM
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CP0931122
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trans-3-(2-((5R)-5-((7-Fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl)-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)-2-oxoethyl)cyclobutanecarboxylic Acid
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C28H32FN3O5
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1
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| 1 |
IC50 = 27 nM
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CP0960429
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cis-3-(2-((5R)-5-((7-Fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl)-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)-2-oxoethyl)cyclobutanecarboxylic Acid
Show/Hide
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C28H32FN3O5
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1
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| 1 |
IC50 = 29 nM
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CP0520885
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N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-(oxan-4-ylmethoxy)benzenesulfonamide
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C25H35NO5S
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1
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| 1 |
IC50 = 30 nM
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CP0960428
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cis-3-(((5R)-5-((7-Fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl)-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)carbonyl)cyclobutanecarboxylic Acid
Show/Hide
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C27H30FN3O5
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1
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| 1 |
IC50 = 31 nM
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CP0396454
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5-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-3-hydroxy-3-methyl-5-oxopentanoic acid
Show/Hide
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C26H32F2N2O6Si
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1
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| 1 |
IC50 = 32 nM
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CP0416508
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N-(3-chloro-4-cyanophenyl)-N'-[1-(cyclopropylmethyl)-3-ethyl-2,4-dioxoquinazolin-6-yl]-3-methylpentanediamide
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C27H28ClN5O4
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1
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| 1 |
IC50 = 32 nM
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CP0885835
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trans-3-(((5R)-5-((7-Fluoro-1,1-dimethyl-2,3-dihydro-1Hinden-5-yl)carbamoyl)-2-methoxy-7,8-dihydro-1,6-naphthyri-din-6(5H)-yl)carbonyl)cyclobutanecarboxylic Acid
Show/Hide
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C27H30FN3O5
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1
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| 1 |
IC50 = 34 nM
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CP0396048
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N-[1-(4-methoxyphenyl)-2-oxo-2-(4-trimethylsilylanilino)ethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
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C25H29N3O4Si
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1
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| 1 |
IC50 = 35 nM
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CP0571812
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N-(4-ethylphenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
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C26H33NO5S
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1
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| 1 |
IC50 = 36 nM
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CP0111082
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(E)-4-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-4-oxobut-2-enoic acid
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C24H26F2N2O5Si
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1
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| 1 |
IC50 = 38 nM
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CP0144907
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(5R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-8-methoxy-4-(3-oxo-1,2-oxazole-5-carbonyl)-3,5-dihydro-2H-1,4-benzoxazepine-5-carboxamide
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C24H25F2N3O6Si
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1
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| 1 |
IC50 = 40 nM
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CP0408940
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(1R)-N-(3,5-difluoro-4-trimethylsilylphenyl)-2-[2-(2,4-dioxo-1,3-thiazolidin-5-yl)acetyl]-6-methoxy-3,4-dihydro-1H-isoquinoline-1-carboxamide
Show/Hide
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C25H27F2N3O5SSi
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1
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| 1 |
IC50 = 41 nM
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CP0544566
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(2S)-N-(4-ethylphenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C26H33NO5S
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1
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| 1 |
IC50 = 41 nM
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CP0577875
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N-(2,4-dimethylphenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C26H33NO5S
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1
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| 1 |
IC50 = 41 nM
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CP0576571
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(2R)-N-(4-ethylphenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C26H33NO5S
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1
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| 1 |
IC50 = 43 nM
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CP0577877
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N-(cyclopropylmethyl)-N-(4-ethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
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C26H31NO5S
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1
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| 1 |
IC50 = 43 nM
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CP0361259
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5-[(5R)-5-[(7-fluoro-1,1-dimethyl-2,3-dihydroinden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-5-oxopentanoic acid
Show/Hide
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C26H30FN3O5
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1
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| 1 |
IC50 = 45 nM
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CP0111081
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5-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-3,3-dimethyl-5-oxopentanoic acid
Show/Hide
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C27H34F2N2O5Si
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1
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| 1 |
IC50 = 46 nM
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CP0488542
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N-cyclobutyl-N-(2,4-dimethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
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C26H31NO5S
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1
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| 1 |
IC50 = 46 nM
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CP0341566
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N-(3-chloro-4-cyanophenyl)-N'-(1,3-diethyl-2,4-dioxoquinazolin-6-yl)-3-methylpentanediamide
Show/Hide
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C25H26ClN5O4
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1
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| 1 |
IC50 = 47 nM
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CP0408147
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N-[1-(4-methoxyphenyl)-2-oxo-2-(4-trimethylsilylanilino)ethyl]-N-methyl-3-oxo-1,2-oxazole-5-carboxamide
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C23H27N3O5Si
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1
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| 1 |
IC50 = 48 nM
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CP0904661
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5-((1R)-1-((4-tert-Butyl-3,5-difluorophenyl)carbamoyl)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-5-oxopentanoic acid
Show/Hide
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C26H30F2N2O5
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1
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| 1 |
IC50 = 49 nM
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CP0127328
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4-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-4-oxobutanoic acid
Show/Hide
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C24H28F2N2O5Si
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1
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| 1 |
IC50 = 54 nM
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CP0412818
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N-(4-cyanophenyl)-N'-(9-ethyl-5,6,7,8-tetrahydrocarbazol-3-yl)-3-methylpentanediamide
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C27H30N4O2
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1
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| 1 |
IC50 = 57 nM
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CP0931121
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5-((1R)-1-((3,5-Difluoro-4-(1-methoxy-2-methylpropan-2-yl)-phenyl)carbamoyl)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-5-oxopentanoic Acid
Show/Hide
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C27H32F2N2O6
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1
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| 1 |
IC50 = 65 nM
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CP0566951
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N-[1-(4-methoxyphenyl)-2-oxo-2-(4-trimethylsilylanilino)ethyl]-N-methyl-1,2-oxazole-5-carboxamide
Show/Hide
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C23H27N3O4Si
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1
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| 1 |
IC50 = 73 nM
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CP0885833
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5-((1R)-1-((7-Fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl)-6-methoxy-3,4-dihydroisoquinolin-2(1H)-yl)-5-oxopentanoic Acid
Show/Hide
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C27H31FN2O5
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1
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| 1 |
IC50 = 74 nM
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CP0954004
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(1-(((5R)-5-((7-Fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl)-2-methoxy-7,8-dihydro-1,6-naphthyridin-6(5H)-yl)carbonyl)azetidin-3-yl)acetic Acid
Show/Hide
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C27H31FN4O5
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1
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| 1 |
IC50 = 78 nM
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CP0477736
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N-(4-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)-3-methylpentanediamide
Show/Hide
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C27H26N4O2
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1
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| 1 |
IC50 = 92 nM
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CP0118634
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N-(3-chloro-4-cyanophenyl)-N'-(2,4-diethyl-3-oxo-1,4-benzoxazin-7-yl)-3-methylpentanediamide
Show/Hide
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C25H27ClN4O4
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1
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| 1 |
IC50 = 100 nM
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CP0488538
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N-(4-ethylphenyl)-N-(2-methylpropyl)-2-(oxan-4-ylmethyl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C27H35NO5S
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1
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| 1 |
IC50 = 101 nM
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CP0579898
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N-(4-fluorophenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C24H28FNO5S
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1
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| 1 |
IC50 = 110 nM
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CP0579899
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N-[4-(dimethylamino)phenyl]-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C26H34N2O5S
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1
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| 1 |
IC50 = 114 nM
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CP0552826
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N-(2,4-difluorophenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C24H27F2NO5S
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1
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| 1 |
IC50 = 118 nM
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CP0124889
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N-[2-(4-tert-butyl-3-chloroanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
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C26H28ClN3O4
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1
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| 1 |
IC50 = 120 nM
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CP0060563
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2-[1-[2,4-dichloro-3-[2-(5-chlorofuran-2-yl)-5-methyl-4-(trifluoromethyl)imidazol-1-yl]phenyl]azetidin-3-yl]acetic acid
Show/Hide
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C20H15Cl3F3N3O3
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1
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| 1 |
IC50 = 120 nM
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CP0402072
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3-[2,4-dichloro-3-[2-(5-chlorofuran-2-yl)-5-methyl-4-[1-(trifluoromethyl)cyclopropyl]imidazol-1-yl]anilino]-2,2-dimethylpropanoic acid
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C23H21Cl3F3N3O3
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1
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| 1 |
IC50 = 120 nM
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CP0098044
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N-(5-benzoyl-4-phenyl-1,3-thiazol-2-yl)-2-(4-ethylsulfonylphenyl)acetamide
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C26H22N2O4S2
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1
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| 1 |
IC50 = 125.89 nM
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CP0394521
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2-[2-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethoxy]acetic acid
Show/Hide
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C24H28F2N2O6Si
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1
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| 1 |
IC50 = 140 nM
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CP0488539
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N-(4-ethylphenyl)-N-(2-methylpropyl)-2-[1-(oxan-4-yl)ethyl]-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C28H37NO5S
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1
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| 1 |
IC50 = 144 nM
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CP0576570
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N-(4-ethylphenyl)-4-fluoro-N-(2-methylpropyl)-2-(oxan-4-yl)-3,4-dihydro-2H-chromene-6-sulfonamide
Show/Hide
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C26H34FNO4S
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1
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| 1 |
IC50 = 146 nM
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CP0551495
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N-(cyclobutylmethyl)-N-(4-ethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C27H33NO5S
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1
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| 1 |
IC50 = 148 nM
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CP0402071
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2-[2,4-dichloro-3-[2-cyclopropyl-5-methyl-4-[1-(trifluoromethyl)cyclopropyl]imidazol-1-yl]phenyl]-2-azaspiro[3.3]heptane-6-carboxylic acid
Show/Hide
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C24H24Cl2F3N3O2
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1
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| 1 |
IC50 = 151 nM
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CP0260504
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N-cyclobutyl-N-(4-ethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C26H31NO5S
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1
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| 1 |
IC50 = 158 nM
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CP0546328
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N-(4-tert-butylphenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C28H37NO5S
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1
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| 1 |
IC50 = 158 nM
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CP0580019
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N-benzyl-N-(4-ethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C29H31NO5S
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1
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| 1 |
IC50 = 175 nM
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CP0580007
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N-(4-ethylphenyl)-2-(4-methyloxan-4-yl)-N-(2-methylpropyl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C27H35NO5S
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1
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| 1 |
IC50 = 185 nM
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CP0550142
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N-[2-[(1,1-dimethyl-2,3-dihydroinden-5-yl)amino]-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
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C27H29N3O4
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1
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| 1 |
IC50 = 190 nM
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CP0566953
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N-[1-(4-methoxyphenyl)-2-oxo-2-(4-trimethylsilylanilino)ethyl]-N-methylfuran-2-carboxamide
Show/Hide
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C24H28N2O4Si
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1
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| 1 |
IC50 = 190 nM
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CP0560135
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N-[4-cyano-3-(trifluoromethyl)phenyl]-N'-(9-ethylcarbazol-3-yl)-3-methylpentanediamide
Show/Hide
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C28H25F3N4O2
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1
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| 1 |
IC50 = 190 nM
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CP0215047
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N-(3-chloro-4-cyanophenyl)-N'-(4-ethyl-2-methyl-3-oxo-1,4-benzoxazin-7-yl)-3-methylpentanediamide
Show/Hide
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C24H25ClN4O4
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1
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| 1 |
IC50 = 200 nM
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CP0526724
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N-(4-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)pentanediamide
Show/Hide
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C26H24N4O2
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1
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| 1 |
IC50 = 200 nM
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CP0219108
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N-[2-(4-tert-butylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
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C25H27N3O4
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1
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| 1 |
IC50 = 210 nM
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CP0082875
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4-[[(1R)-2-(3,5-difluoro-4-trimethylsilylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-methylamino]-4-oxobutanoic acid
Show/Hide
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C23H28F2N2O5Si
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1
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| 1 |
IC50 = 220 nM
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CP0248827
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2-[[2-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-2-oxoethyl]-methylamino]acetic acid
Show/Hide
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C25H31F2N3O5Si
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1
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| 1 |
IC50 = 220 nM
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CP0260503
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N-(3-fluorophenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C24H28FNO5S
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1
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| 1 |
IC50 = 255 nM
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CP0580017
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N-(4-ethylphenyl)-7-(hydroxymethyl)-N-(2-methylpropyl)-6-(oxan-4-ylmethoxy)naphthalene-2-sulfonamide
Show/Hide
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C29H37NO5S
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1
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| 1 |
IC50 = 260 nM
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CP0219107
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N-[2-(4-tert-butylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
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C26H29N3O4
|
1
|
| 1 |
IC50 = 270 nM
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CP0580078
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2-(oxan-4-yl)-6-[2-[2-(trifluoromethyl)phenyl]pyrrolidin-1-yl]sulfonyl-2,3-dihydrochromen-4-one
Show/Hide
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C25H26F3NO5S
|
1
|
| 1 |
IC50 = 287 nM
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CP0552824
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N-(4-cyanophenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C25H28N2O5S
|
1
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| 1 |
IC50 = 310 nM
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CP0579635
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N-(4-ethylphenyl)-2-(oxan-4-yl)-4-oxo-N-(2,2,2-trifluoroethyl)-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C24H26F3NO5S
|
1
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| 1 |
IC50 = 318 nM
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CP0427356
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(Z)-4-[(1R)-1-[(3,5-difluoro-4-trimethylsilylphenyl)carbamoyl]-6-methoxy-3,4-dihydro-1H-isoquinolin-2-yl]-4-oxobut-2-enoic acid
Show/Hide
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C24H26F2N2O5Si
|
1
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| 1 |
IC50 = 320 nM
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CP0552825
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N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-N-[[2-(trifluoromethyl)phenyl]methyl]-2,3-dihydrochromene-6-sulfonamide
Show/Hide
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C26H30F3NO5S
|
1
|
| 1 |
IC50 = 321 nM
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CP0189183
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N-[2-(4-tert-butylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-6-oxo-N-propyl-1H-pyridine-3-carboxamide
Show/Hide
|
C28H33N3O4
|
1
|
| 1 |
IC50 = 370 nM
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|
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CP0549915
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N-(4-ethylphenyl)-N-(2-methylpropyl)-2-(1-methylsulfonylpiperidin-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C27H36N2O6S2
|
1
|
| 1 |
IC50 = 372 nM
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CP0564992
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N-[(1S)-2-(3,5-difluoro-4-trimethylsilylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-3-oxo-1,2-oxazole-5-carboxamide
Show/Hide
|
C23H25F2N3O5Si
|
1
|
| 1 |
IC50 = 420 nM
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CP0552822
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N-(4-ethylphenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-3-oxo-1H-isoindole-5-sulfonamide
Show/Hide
|
C25H32N2O4S
|
1
|
| 1 |
IC50 = 429 nM
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|
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CP0252169
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N-[2-(4-tert-butylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-3-oxo-1,2-oxazole-5-carboxamide
Show/Hide
|
C24H27N3O5
|
1
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| 1 |
IC50 = 540 nM
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CP0542965
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N-(4-ethylphenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxochromene-6-sulfonamide
Show/Hide
|
C26H31NO5S
|
1
|
| 1 |
IC50 = 567 nM
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CP0488541
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N-(1-benzothiophen-2-yl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C26H29NO5S2
|
1
|
| 1 |
IC50 = 636 nM
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|
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CP0260501
|
N-(4-ethylphenyl)-N-(2-methylpropyl)-7-(oxan-4-ylmethoxy)-1-oxo-2,3-dihydroindene-4-sulfonamide
Show/Hide
|
C27H35NO5S
|
1
|
| 1 |
IC50 = 794 nM
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|
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CP0564978
|
N-[2-(4-tert-butylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-1,2-oxazole-5-carboxamide
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
IC50 = 870 nM
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|
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CP0549921
|
N-(4-ethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C22H25NO5S
|
1
|
| 1 |
IC50 = 975 nM
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|
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CP0544567
|
N-(6-fluoro-2,3-dihydro-1H-inden-1-yl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C27H32FNO5S
|
1
|
| 1 |
IC50 = 1016 nM
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|
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CP0408677
|
N-[2-(4-tert-butylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methylfuran-2-carboxamide
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
IC50 = 1100 nM
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|
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CP0552823
|
2-(1-cyclopentylsulfonylpiperidin-4-yl)-N-(4-ethylphenyl)-N-(2-methylpropyl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C31H42N2O6S2
|
1
|
| 1 |
IC50 = 1147 nM
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|
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CP0118610
|
N-(3-chloro-4-cyanophenyl)-N'-(4-ethyl-3-oxo-1,4-benzoxazin-7-yl)-3-methylpentanediamide
Show/Hide
|
C23H23ClN4O4
|
1
|
| 1 |
IC50 = 1400 nM
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|
|
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CP0577876
|
N-(2,4-dimethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C22H25NO5S
|
1
|
| 1 |
IC50 = 1424 nM
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|
|
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CP0189181
|
N-[1-(4-methoxyphenyl)-2-oxo-2-(4-propan-2-ylanilino)ethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C25H27N3O4
|
1
|
| 1 |
IC50 = 1600 nM
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|
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CP0335252
|
N-(4-cyanophenyl)-2-[[2-[(9-ethylcarbazol-3-yl)amino]-2-oxoethyl]-methylamino]acetamide
Show/Hide
|
C26H25N5O2
|
1
|
| 1 |
IC50 = 1600 nM
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|
|
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CP0552821
|
oxan-4-ylmethyl 7-[(4-ethylphenyl)-(2-methylpropyl)sulfamoyl]-3-(oxan-4-ylmethoxy)naphthalene-2-carboxylate
Show/Hide
|
C35H45NO7S
|
1
|
| 1 |
IC50 = 1762 nM
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|
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CP0260502
|
2-(3,5-dimethyl-1,2-oxazol-4-yl)-N-(4-ethylphenyl)-N-(2-methylpropyl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C26H30N2O5S
|
1
|
| 1 |
IC50 = 1998 nM
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|
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CP0885836
|
(R)-2-(3-(5-(7-fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-ylcarbamoyl)-2-methoxy-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carbonyl)azetidin-1-yl)acetic acid
Show/Hide
|
C27H31FN4O5
|
1
|
| 1 |
IC50 = 2100 nM
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|
|
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CP0260500
|
N-(4-ethylphenyl)-N-(2-methylpropyl)-4-(oxan-4-ylmethoxy)-5-oxo-7,8-dihydro-6H-naphthalene-1-sulfonamide
Show/Hide
|
C28H37NO5S
|
1
|
| 1 |
IC50 = 2435 nM
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|
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CP0580018
|
2-[1-(cyclopentanecarbonyl)piperidin-4-yl]-N-(4-ethylphenyl)-N-(2-methylpropyl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C32H42N2O5S
|
1
|
| 1 |
IC50 = 2509 nM
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|
|
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CP0542963
|
methyl 7-[(4-ethylphenyl)-(2-methylpropyl)sulfamoyl]-3-(oxan-4-ylmethoxy)naphthalene-2-carboxylate
Show/Hide
|
C30H37NO6S
|
1
|
| 1 |
IC50 = 3612 nM
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|
|
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CP0118636
|
N-(3-chloro-4-cyanophenyl)-N'-(1-ethylindol-5-yl)-3-methylpentanediamide
Show/Hide
|
C23H23ClN4O2
|
1
|
| 1 |
IC50 = 4000 nM
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|
|
|
CP0549844
|
N-(4-cyanophenyl)-2-[2-[(9-ethylcarbazol-3-yl)amino]-2-oxoethoxy]acetamide
Show/Hide
|
C25H22N4O3
|
1
|
| 1 |
IC50 = 4200 nM
|
|
|
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CP0488540
|
N-(2-fluorophenyl)-N-(2-methylpropyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C24H28FNO5S
|
1
|
| 1 |
IC50 = 4896 nM
|
|
|
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CP0341567
|
N-(3-chloro-4-cyanophenyl)-N'-(3-ethyl-2-oxo-1,3-benzoxazol-6-yl)-3-methylpentanediamide
Show/Hide
|
C22H21ClN4O4
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0341568
|
N-(3-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)-3-methylpentanediamide
Show/Hide
|
C27H26N4O2
|
1
|
| 1 |
IC50 = 6300 nM
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|
|
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CP0557981
|
N-(4-cyanophenyl)-3-methyl-N'-(6,7,8,9-tetrahydro-5H-carbazol-3-yl)pentanediamide
Show/Hide
|
C25H26N4O2
|
1
|
| 1 |
IC50 = 7700 nM
|
|
|
|
CP0198871
|
N-(4-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)-3,3-dimethylpentanediamide
Show/Hide
|
C28H28N4O2
|
1
|
| 1 |
IC50 = 7800 nM
|
|
|
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CP0577874
|
N-(4-ethylphenyl)-N-(2-methylpropyl)-4-oxo-2-piperidin-4-yl-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C26H34N2O4S
|
1
|
| 1 |
IC50 = 8614 nM
|
|
|
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CP0260505
|
N-[(5-ethylsulfonylpyridin-2-yl)methyl]-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C22H26N2O7S2
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
|
CP0551496
|
N-(4-ethylphenyl)-2-(oxan-4-yl)-N-(oxetan-3-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
Show/Hide
|
C25H29NO6S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0576569
|
7-[(4-ethylphenyl)-(2-methylpropyl)sulfamoyl]-3-(oxan-4-ylmethoxy)naphthalene-2-carboxylic acid
Show/Hide
|
C29H35NO6S
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0576572
|
6-[(6-ethyl-3-methyl-3,4-dihydro-2H-quinolin-1-yl)sulfonyl]-2-(oxan-4-yl)-2,3-dihydrochromen-4-one
Show/Hide
|
C26H31NO5S
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
|
CP0577873
|
tert-butyl 4-[6-[(4-ethylphenyl)-(2-methylpropyl)sulfamoyl]-4-oxo-2,3-dihydrochromen-2-yl]piperidine-1-carboxylate
Show/Hide
|
C31H42N2O6S
|
1
|
| 1 |
IC50 > 10000 nM
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|
|
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CP0412820
|
N-(4-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)-N,N',3-trimethylpentanediamide
Show/Hide
|
C29H30N4O2
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
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CP0331274
|
N-[2-(4-tert-butylanilino)-1-(4-methoxy-2-methylphenyl)-2-oxoethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 = 21000 nM
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|
|
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CP0109734
|
N-[3-(4-tert-butylanilino)-1-(4-methoxyphenyl)-3-oxopropyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 > 30000 nM
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|
|
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CP0189182
|
N-[1-(4-tert-butylanilino)-3-(4-methoxyphenyl)-1-oxopropan-2-yl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0482021
|
N-[1-(4-methoxyphenyl)-2-(4-methylanilino)-2-oxoethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C23H23N3O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0564974
|
N-[2-(4-tert-butyl-N-methylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0564993
|
N-[3-(4-tert-butylanilino)-2-(4-methoxyphenyl)-3-oxopropyl]-N-methyl-6-oxo-1H-pyridine-3-carboxamide
Show/Hide
|
C27H31N3O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
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CP0365210
|
N'-(9-ethylcarbazol-3-yl)-3-methyl-N-phenylpentanediamide
Show/Hide
|
C26H27N3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0365211
|
N-(2-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)-3-methylpentanediamide
Show/Hide
|
C27H26N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0412819
|
N-(9-ethylcarbazol-3-yl)-N'-(4-fluorophenyl)-3-methylpentanediamide
Show/Hide
|
C26H26FN3O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0412821
|
N-(4-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)butanediamide
Show/Hide
|
C25H22N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0526723
|
N-(4-cyanophenyl)-N'-(9-ethylcarbazol-3-yl)hexanediamide
Show/Hide
|
C27H26N4O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0545451
|
6-[2-[5-cyclopropyl-3-(3,5-dichloropyridin-4-yl)-1,2-oxazol-4-yl]-7-azaspiro[3.5]non-2-en-7-yl]-4-(trifluoromethyl)quinoline-2-carboxylic acid
Show/Hide
|
C30H23Cl2F3N4O3
|
1
|
| 1 |
IC50 > 40000 nM
|
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|
