Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-cyclobutyl-N-(2,4-dimethylphenyl)-2-(oxan-4-yl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
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 PubChem ID
CID: 142380354
Canonical SMILES
Cc1ccc(N(C2CCC2)S(=O)(=O)c2ccc3OC(CC(=O)c3c2)C2CCOCC2)c(C)c1
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Compound Formula C26H31NO5S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 46 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12 nM