Brief Information of the Compound and Protein
Compound Name
2-(3,5-dimethyl-1,2-oxazol-4-yl)-N-(4-ethylphenyl)-N-(2-methylpropyl)-4-oxo-2,3-dihydrochromene-6-sulfonamide
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PubChem ID
CID: 142380334
Canonical SMILES
CCc1ccc(cc1)N(CC(C)C)S(=O)(=O)c1ccc2OC(CC(=O)c2c1)c1c(C)noc1C
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Compound Formula C26H30N2O5S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 1998 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 458 nM