Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(3-chloro-4-cyanophenyl)-N'-(4-ethyl-2-methyl-3-oxo-1,4-benzoxazin-7-yl)-3-methylpentanediamide
    Show/Hide
 PubChem ID
CID: 118658608
Canonical SMILES
CCN1C(=O)C(C)Oc2cc(NC(=O)CC(C)CC(=O)Nc3ccc(C#N)c(Cl)c3)ccc12
    Show/Hide
Compound Formula C24H25ClN4O4
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 13 nM