Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[(1R)-2-(3,5-difluoro-4-trimethylsilylanilino)-1-(4-methoxyphenyl)-2-oxoethyl]-methylamino]-4-oxobutanoic acid
    Show/Hide
 PubChem ID
CID: 145967121
Canonical SMILES
COc1ccc(cc1)[C@@H](N(C)C(=O)CCC(O)=O)C(=O)Nc1cc(F)c(c(F)c1)[Si](C)(C)C
    Show/Hide
Compound Formula C23H28F2N2O5Si
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7.5 nM