Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5R)-6-acetyl-2-methoxy-N-[4-[(2-methoxyphenyl)methoxy]phenyl]-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
    Show/Hide
 PubChem ID
CID: 138393322
Canonical SMILES
COc1ccc2[C@@H](N(CCc2n1)C(C)=O)C(=O)Nc1ccc(OCc2ccccc2OC)cc1
    Show/Hide
Compound Formula C26H27N3O5
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 8100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 53 nM
2 IC50 = 44 nM