Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[1,3-bis(cyclopropylmethyl)-2,4-dioxoquinazolin-6-yl]-N'-(3-chloro-4-cyanophenyl)-3-methylpentanediamide
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 PubChem ID
CID: 78324933
Canonical SMILES
CC(CC(=O)Nc1ccc(C#N)c(Cl)c1)CC(=O)Nc1ccc2n(CC3CC3)c(=O)n(CC3CC3)c(=O)c2c1
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Compound Formula C29H30ClN5O4
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.9 nM