Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(5R)-5-[[1-[(2-ethoxyphenyl)methyl]-2,3-dihydroindol-5-yl]carbamoyl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-5-oxopentanoic acid
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 PubChem ID
CID: 155518209
Canonical SMILES
CCOc1ccccc1CN1CCc2cc(NC(=O)[C@@H]3N(CCc4nc(OC)ccc34)C(=O)CCCC(O)=O)ccc12
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Compound Formula C32H36N4O6
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 68 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 2.1 nM
2 IC50 = 6 nM