Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4-(2H-tetrazol-5-yl)cyclohexyl)((3aR,9bR)-7-(2-fluoro-6-(trifluoromethyl)benzyloxy)-9b-(4-fluorophenylsulfonyl)-4,5-dihydro-1H-benzo[e]indol-3(2H,3aH,9bH)-yl)methanone
    Show/Hide
Canonical SMILES
O=C([C@H]1CC[C@H](c2nn[nH]n2)CC1)N1CC[C@@]2(S(=O)(=O)c3ccc(F)cc3)c3ccc(OCc4c(F)cccc4C(F)(F)F)cc3CC[C@@H]12
    Show/Hide
Compound Formula C34H32F5N5O4S
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 8.5 nM
   TI
   LI
   LO
   TS