Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-2-(3-(5-(7-fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-ylcarbamoyl)-2-methoxy-5,6,7,8-tetrahydro-1,6-naphthyridine-6-carbonyl)azetidin-1-yl)acetic acid
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 PubChem ID
CID: 121316369
Canonical SMILES
COc1ccc2c(n1)CCN(C(=O)C1CN(CC(=O)O)C1)[C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C
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Compound Formula C27H31FN4O5
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS