Brief Information of the Compound and Protein
Compound Name
4-[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-[[2-fluoro-6-(trifluoromethyl)phenyl]methoxy]-2,3a,4,5-tetrahydro-1H-benzo[e]indole-3-carbonyl]piperidine-1-carboxamide
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PubChem ID
CID: 155307789
Canonical SMILES
NC(=O)N1CCC(CC1)C(=O)N1CC[C@@]2([C@H]1CCc1cc(OCc3c(F)cccc3C(F)(F)F)ccc21)S(=O)(=O)c1ccc(F)cc1
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Compound Formula C33H32F5N3O5S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
EC50 = 5.6 nM
   TI
   LI
   LO
   TS