Brief Information of the Compound and Protein
Compound Name
6-acetyl-N-[4-[(2-chlorophenyl)methoxy]phenyl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridine-5-carboxamide
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PubChem ID
CID: 155523977
Canonical SMILES
COc1ccc2C(N(CCc2n1)C(C)=O)C(=O)Nc1ccc(OCc2ccccc2Cl)cc1
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Compound Formula C25H24ClN3O4
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 > 10000 nM
2 IC50 = 290 nM