Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(5R)-5-[(7-fluoro-1,1-dimethyl-2,3-dihydroinden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridin-6-yl]-5-oxopentanoic acid
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 PubChem ID
CID: 87055114
Canonical SMILES
COc1ccc2[C@@H](N(CCc2n1)C(=O)CCCC(O)=O)C(=O)Nc1cc2CCC(C)(C)c2c(F)c1
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Compound Formula C26H30FN3O5
Compound Structure
Protein Name
 Protein Info 
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 45 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 31 nM
2 IC50 = 3.3 nM