Brief Information of the Compound and Protein
Compound Name
1,1,1,3,3,3-hexafluoro-2-[4-(4-fluorophenyl)sulfonyl-2,3-dihydro-1,4-benzoxazin-7-yl]propan-2-ol
    Show/Hide
PubChem ID
CID: 145965098
Canonical SMILES
OC(c1ccc2N(CCOc2c1)S(=O)(=O)c1ccc(F)cc1)(C(F)(F)F)C(F)(F)F
    Show/Hide
Compound Formula C17H12F7NO4S
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
EC50 = 203 nM
   TI
   LI
   LO
   TS