Brief Information of the Compound and Protein
Compound Name
[(3R)-3-[4-[[2-chloro-6-(trifluoromethyl)phenyl]methoxy]phenyl]-3-(4-fluorophenyl)sulfonylpyrrolidin-1-yl]-(1,1-dioxothian-4-yl)methanone
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PubChem ID
CID: 156019728
Canonical SMILES
Fc1ccc(cc1)S(=O)(=O)[C@]1(CCN(C1)C(=O)C1CCS(=O)(=O)CC1)c1ccc(OCc2c(Cl)cccc2C(F)(F)F)cc1
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Compound Formula C30H28ClF4NO6S2
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
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Nuclear receptor
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Nuclear hormone receptor subfamily 1
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Nuclear hormone receptor subfamily 1 group F
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Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
EC50 = 31 nM
   TI
   LI
   LO
   TS