Brief Information of the Compound and Protein
Compound Name
N-[1-(4-methoxyphenyl)-2-oxo-2-(4-trimethylsilylanilino)ethyl]-N-methyl-1,2-oxazole-5-carboxamide
    Show/Hide
PubChem ID
CID: 140781127
Canonical SMILES
COc1ccc(cc1)C(N(C)C(=O)c1ccno1)C(=O)Nc1ccc(cc1)[Si](C)(C)C
    Show/Hide
Compound Formula C23H27N3O4Si
Compound Structure
Protein Name
Nuclear receptor ROR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group F
>
Nuclear hormone receptor subfamily 1 group F member 3
Uniprot ID
P51449
Gene Name
RORC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000001 Jurkat Homo sapiens (Human)  1
1
IC50 = 73 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM