| Compound ID |
Compound Name |
Compound Formula |
|
CP0412063
|
5-fluoro-2-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole-2-carbonyl]-N-(2,2,2-trifluoroethyl)-1,3-benzothiazole-6-carboxamide
Show/Hide
|
C14H10F4N6O5S2
|
2
|
| 1 |
IC50 < 0.5 nM
|
|
|
| 2 |
IC50 = 50 nM
|
|
|
|
CP0412064
|
2-[5-fluoro-6-(1-oxo-2,3-dihydroisoindol-5-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C19H13FN6O5S2
|
2
|
| 1 |
IC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
|
CP0412065
|
2-[6-fluoro-5-(1-oxo-2,3-dihydroisoindol-5-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C19H13FN6O5S2
|
2
|
| 1 |
IC50 < 0.5 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0517674
|
4-[6-fluoro-2-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole-2-carbonyl]-1,3-benzothiazol-5-yl]-N-(2,2,2-trifluoroethyl)benzamide
Show/Hide
|
C20H14F4N6O5S2
|
2
|
| 1 |
IC50 < 0.5 nM
|
|
|
| 2 |
IC50 = 200 nM
|
|
|
|
CP0519336
|
4-[2-fluoro-4-[5-fluoro-2-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole-2-carbonyl]-1,3-benzothiazol-6-yl]benzoyl]morpholine
Show/Hide
|
C22H18F2N6O6S2
|
2
|
| 1 |
IC50 = 0.9 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0401877
|
2-[5-fluoro-6-(6-fluoropyridin-3-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C16H10F2N6O4S2
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 20 nM
|
|
|
|
CP0414559
|
US9249096, 65
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|
C19H24Cl2N2O4
|
1
|
| 1 |
IC50 = 1.598 nM
|
|
|
|
CP0519213
|
US9249096, 45
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|
C19H24Cl2N2O3
|
1
|
| 1 |
IC50 = 2.71 nM
|
|
|
|
CP0414555
|
US9249096, 42
Show/Hide
|
C18H22Cl2N2O3
|
1
|
| 1 |
IC50 = 2.932 nM
|
|
|
|
CP0414556
|
US9249096, 44
Show/Hide
|
C22H22Cl2N2O3
|
1
|
| 1 |
IC50 = 3.216 nM
|
|
|
|
CP0545799
|
US9249096, 46
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|
C18H22Cl2N2O3
|
1
|
| 1 |
IC50 = 3.255 nM
|
|
|
|
CP0576448
|
US9249096, 47
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|
C21H19Cl3N2O3
|
1
|
| 1 |
IC50 = 3.304 nM
|
|
|
|
CP0446340
|
US9249096, 40
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|
C21H20Cl2N2O3
|
2
|
| 1 |
IC50 = 3.6 nM
|
|
|
| 2 |
IC50 = 3.647 nM
|
|
|
|
CP0490191
|
US9169240, 44
Show/Hide
|
C24H23FN4O2S
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0323320
|
2-(6-phenyl-1,3-benzothiazole-2-carbonyl)-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
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|
C17H13N5O4S2
|
3
|
| 1 |
IC50 = 5 nM
|
|
|
| 2 |
IC50 = 60 nM
|
|
|
| 3 |
IC50 = 100 nM
|
|
|
|
CP0578099
|
US9249096, 39
Show/Hide
|
C18H20Cl2N2O3
|
1
|
| 1 |
IC50 = 5.095 nM
|
|
|
|
CP0545800
|
US9249096, 53
Show/Hide
|
C22H21Cl3N2O3
|
1
|
| 1 |
IC50 = 5.239 nM
|
|
|
|
CP0520776
|
N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-5-oxo-1-(2-phenoxyethyl)-2H-pyrrole-3-carboxamide
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|
C22H22Cl2N2O4
|
2
|
| 1 |
IC50 = 5.4 nM
|
|
|
| 2 |
IC50 = 826 nM
|
|
|
|
CP0414557
|
US9249096, 51
Show/Hide
|
C21H19Cl2FN2O3
|
1
|
| 1 |
IC50 = 5.522 nM
|
|
|
|
CP0519214
|
US9249096, 64
Show/Hide
|
C22H21Cl2FN2O3
|
1
|
| 1 |
IC50 = 5.607 nM
|
|
|
|
CP0483314
|
US9249096, 60
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|
C21H18Cl4N2O3
|
1
|
| 1 |
IC50 = 5.637 nM
|
|
|
|
CP0483313
|
US9249096, 55
Show/Hide
|
C20H26Cl2N2O3
|
1
|
| 1 |
IC50 = 5.803 nM
|
|
|
|
CP0544401
|
US9249096, 50
Show/Hide
|
C21H19Cl2FN2O3
|
1
|
| 1 |
IC50 = 5.99 nM
|
|
|
|
CP0058220
|
(2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-2-yl (2S)-2-formamido-4-methylpentanoate
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|
C29H53NO5
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0414558
|
US9249096, 57
Show/Hide
|
C18H22Cl2N2O4
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0559714
|
US9169240, 64
Show/Hide
|
C24H16ClFN4O2S
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0556071
|
US8993557, 16
Show/Hide
|
C20H17FN2O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0419936
|
US9139578, 13
Show/Hide
|
C21H22N6O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0419937
|
US9139578, 14
Show/Hide
|
C22H24N6O5S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0422578
|
US9139578, 19
Show/Hide
|
C25H17F3N4O5S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0422579
|
US9139578, 15
Show/Hide
|
C21H23N7O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0435075
|
US9139578, 16
Show/Hide
|
C25H19F3N6O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0435077
|
US9139578, 11
Show/Hide
|
C20H17N7O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0440540
|
US9139578, 18
Show/Hide
|
C21H18N4O5S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0440542
|
US9139578, 6
Show/Hide
|
C21H21FN8O6S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0478135
|
US9139578, 20
Show/Hide
|
C26H27N5O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0493281
|
US9139578, 3
Show/Hide
|
C22H17FN8O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0495011
|
US9139578, 17
Show/Hide
|
C24H25N5O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0509032
|
US9139578, 21
Show/Hide
|
C24H18FN5O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0512078
|
US9139578, 8
Show/Hide
|
C22H20FN9O5S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0518899
|
US9139578, 2
Show/Hide
|
C24H17F4N7O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0523307
|
US9139578, 4
Show/Hide
|
C24H21FN8O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0525119
|
US9139578, 22
Show/Hide
|
C28H17F4N5O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0560980
|
US9139578, 5
Show/Hide
|
C19H18FN7O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0560981
|
US9139578, 7
Show/Hide
|
C23H18F2N8O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0568967
|
US9139578, 10
Show/Hide
|
C18H16FN7O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0573352
|
US9139578, 9
Show/Hide
|
C21H15FN6O5S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0197531
|
US8754113, I-1-85
Show/Hide
|
C17H15N5O3S2
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 400 nM
|
|
|
|
CP0419294
|
US9169240, 21
Show/Hide
|
C23H22N4O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0419297
|
US9169240, 29
Show/Hide
|
C17H12FN5O4S2
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 < 200 nM
|
|
|
|
CP0419298
|
US9169240, 30
Show/Hide
|
C19H16N6O6S2
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 400 nM
|
|
|
| 3 |
IC50 = 700 nM
|
|
|
|
CP0429131
|
US9169240, 55
Show/Hide
|
C20H14FN5O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0463386
|
US9169240, 12
Show/Hide
|
C17H11FN4O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0472812
|
US9169240, 83
Show/Hide
|
C20H16N6O5S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0478194
|
US9169240, 15
Show/Hide
|
C28H29FN4O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0478195
|
US9169240, 17
Show/Hide
|
C28H23FN4O2S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0483068
|
US9169240, 54
Show/Hide
|
C20H14FN5O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0490190
|
US9169240, 39
Show/Hide
|
C24H21N5O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0495568
|
US9169240, 20
Show/Hide
|
C26H26N4O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0516839
|
US9169240, 10
Show/Hide
|
C20H12N4O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0516840
|
US9169240, 13
Show/Hide
|
C28H21F3N4O2S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0517890
|
US9169240, 84
Show/Hide
|
C22H16F3N5O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0518629
|
US9169240, 82
Show/Hide
|
C21H15F2N5O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0519550
|
US9169240, 9
Show/Hide
|
C27H18N4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0519551
|
US9169240, 14
Show/Hide
|
C25H16FN5O2S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0556994
|
US9169240, 11
Show/Hide
|
C19H14N4O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0560974
|
US9169240, 51
Show/Hide
|
C21H16N6O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0561366
|
US9169240, 2
Show/Hide
|
C20H13N5O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0561491
|
US9169240, 50
Show/Hide
|
C21H16N4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0563208
|
US9169240, 5
Show/Hide
|
C17H12N4O4S2
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0563209
|
US9169240, 18
Show/Hide
|
C26H25FN4O4S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0563210
|
US9169240, 23
Show/Hide
|
C29H23F3N4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0570764
|
US9169240, 7
Show/Hide
|
C25H20N6O2S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0570765
|
US9169240, 53
Show/Hide
|
C20H15N5O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0410978
|
N-[3-(3,4-dichlorophenyl)propyl]-1-ethyl-4-(methylamino)-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C17H21Cl2N3O2
|
2
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 3020 nM
|
|
|
|
CP0384139
|
5-[[5-[methylsulfonyl-[6-[4-(morpholine-4-carbonyl)phenyl]-1,3-benzothiazol-2-yl]methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-thiazolidine-2,4-dione
Show/Hide
|
C26H23N5O7S3
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 < 22 nM
|
|
|
| 3 |
IC50 = 94 nM
|
|
|
|
CP0384150
|
2-[2-methoxyethylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C20H21N5O6S3
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 370 nM
|
|
|
| 3 |
IC50 = 900 nM
|
|
|
|
CP0384151
|
2-[(6-phenyl-1,3-benzothiazol-2-yl)-propan-2-ylsulfonylmethyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C20H21N5O5S3
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 360 nM
|
|
|
| 3 |
IC50 = 620 nM
|
|
|
|
CP0384152
|
2-[benzylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C24H21N5O5S3
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 76 nM
|
|
|
| 3 |
IC50 = 77 nM
|
|
|
|
CP0384153
|
2-[benzylsulfonyl-[6-(3-chlorophenyl)-1,3-benzothiazol-2-yl]methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C24H20ClN5O5S3
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 53 nM
|
|
|
| 3 |
IC50 = 66 nM
|
|
|
|
CP0384154
|
2-[methylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C18H17N5O5S3
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 47 nM
|
|
|
| 3 |
IC50 = 170 nM
|
|
|
|
CP0384200
|
2-[benzylsulfonyl-[6-(3,4-dichlorophenyl)-1,3-benzothiazol-2-yl]methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C24H19Cl2N5O5S3
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
| 3 |
IC50 = 150 nM
|
|
|
|
CP0421688
|
2-[(6-phenyl-1,3-benzothiazol-2-yl)-(3,3,3-trifluoropropylsulfonyl)methyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C20H18F3N5O5S3
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 58 nM
|
|
|
| 3 |
IC50 = 100 nM
|
|
|
|
CP0421749
|
4-[2-[benzylsulfonyl-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-benzothiazol-6-yl]-2-chloro-N,N-dimethylbenzamide
Show/Hide
|
C27H25ClN6O6S3
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 1190 nM
|
|
|
| 3 |
IC50 = 8000 nM
|
|
|
|
CP0421750
|
5-methyl-5-[[5-[methylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-1,3,4-oxadiazol-2-yl]methyl]imidazolidine-2,4-dione
Show/Hide
|
C22H19N5O5S2
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 160 nM
|
|
|
| 3 |
IC50 = 380 nM
|
|
|
|
CP0455148
|
4-[4-[2-[benzylsulfonyl-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-benzothiazol-6-yl]-2-chlorobenzoyl]morpholine
Show/Hide
|
C29H27ClN6O7S3
|
3
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
| 3 |
IC50 = 4200 nM
|
|
|
|
CP0482586
|
5-[[5-[methylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-thiazolidine-2,4-dione
Show/Hide
|
C21H16N4O5S3
|
3
|
| 1 |
IC50 < 10 nM
|
|
|
| 2 |
IC50 = 53 nM
|
|
|
| 3 |
IC50 = 910 nM
|
|
|
|
CP0429133
|
US9169240, 87
Show/Hide
|
C20H14BrN5O3S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0517884
|
US9169240, 8
Show/Hide
|
C21H15N5O2S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0574824
|
US8993557, 41
Show/Hide
|
C21H16F4N2O3
|
1
|
| 1 |
IC50 = 11.06 nM
|
|
|
|
CP0424149
|
US8993557, 32
Show/Hide
|
C21H16ClF3N2O3
|
1
|
| 1 |
IC50 = 11.27 nM
|
|
|
|
CP0472809
|
US9169240, 19
Show/Hide
|
C27H28N4O2S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0478196
|
US9169240, 45
Show/Hide
|
C26H28N4O2S
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0441835
|
US9493412, 21
Show/Hide
|
C21H24Cl2N4O4
|
1
|
| 1 |
IC50 = 15.38 nM
|
|
|
|
CP0557014
|
US9169240, 41
Show/Hide
|
C26H17N5O4S
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0556073
|
US8993557, 21
Show/Hide
|
C20H18N2O3
|
1
|
| 1 |
IC50 = 17.92 nM
|
|
|
|
CP0517885
|
US9169240, 43
Show/Hide
|
C24H23FN4O2S
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0560973
|
US9169240, 47
Show/Hide
|
C21H13N5O5S
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0465979
|
N-[3-(3,4-dichlorophenyl)propyl]-1-ethyl-5-oxo-4-(2-propan-2-yloxyethylamino)-2H-pyrrole-3-carboxamide
Show/Hide
|
C21H29Cl2N3O3
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
IC50 = 945 nM
|
|
|
|
CP0480002
|
N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-5-oxo-1-[3-(2-oxopyrrolidin-1-yl)propyl]-2H-pyrrole-3-carboxamide
Show/Hide
|
C21H25Cl2N3O4
|
2
|
| 1 |
IC50 = 19 nM
|
|
|
| 2 |
IC50 = 2440 nM
|
|
|
|
CP0419300
|
US9169240, 42
Show/Hide
|
C24H26N4OS
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0468661
|
2-[6-(3-oxo-1,2-dihydroisoindol-5-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C19H14N6O5S2
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 800 nM
|
|
|
|
CP0468663
|
US9169240, 27
Show/Hide
|
C18H15N5O4S2
|
4
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 23 nM
|
|
|
| 3 |
IC50 = 1000 nM
|
|
|
| 4 |
IC50 = 7000 nM
|
|
|
|
CP0482818
|
[5-[(methylsulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]-(6-phenyl-1,3-benzothiazol-2-yl)methanone
Show/Hide
|
C18H15N5O4S2
|
2
|
| 1 |
IC50 = 20 nM
|
|
|
| 2 |
IC50 = 100 nM
|
|
|
|
CP0455147
|
methyl N-[4-[2-[benzylsulfonyl-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-benzothiazol-6-yl]phenyl]carbamate
Show/Hide
|
C26H24N6O7S3
|
3
|
| 1 |
IC50 = 21 nM
|
|
|
| 2 |
IC50 = 240 nM
|
|
|
| 3 |
IC50 = 300 nM
|
|
|
|
CP0557015
|
US9169240, 57
Show/Hide
|
C20H14N4O4S
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0555891
|
US9493412, 29
Show/Hide
|
C21H22N2O5
|
1
|
| 1 |
IC50 = 22.08 nM
|
|
|
|
CP0519335
|
US9169240, 49
Show/Hide
|
C18H13N5O3S
|
3
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 = 30 nM
|
|
|
| 3 |
IC50 = 1000 nM
|
|
|
|
CP0410977
|
N-[3-(3,4-dichlorophenyl)propyl]-1-ethyl-5-oxo-4-(3-piperidin-1-ylpropylamino)-2H-pyrrole-3-carboxamide
Show/Hide
|
C24H34Cl2N4O2
|
2
|
| 1 |
IC50 = 25 nM
|
|
|
| 2 |
IC50 = 4210 nM
|
|
|
|
CP0563852
|
US9169240, 68
Show/Hide
|
C20H16N4O5S
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0451351
|
US9493412, 18
Show/Hide
|
C19H18N2O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0554798
|
US9493412, 9
Show/Hide
|
C19H16Cl2N2O4
|
1
|
| 1 |
IC50 = 27.05 nM
|
|
|
|
CP0458542
|
US9493412, 48
Show/Hide
|
C27H23F2N3O4
|
1
|
| 1 |
IC50 = 27.08 nM
|
|
|
|
CP0518628
|
US9169240, 75
Show/Hide
|
C21H16F3N5O3S
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0557017
|
US9169240, 89
Show/Hide
|
C16H10N4O2S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0410979
|
N-[3-(3,4-dichlorophenyl)propyl]-2-(2,2-dimethylpropyl)-4-hydroxy-1-methyl-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C20H26Cl2N2O3
|
2
|
| 1 |
IC50 = 29 nM
|
|
|
| 2 |
IC50 = 1770 nM
|
|
|
|
CP0410980
|
N-[3-(3,4-dichlorophenyl)propyl]-1-ethyl-4-hydroxy-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C16H18Cl2N2O3
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 3520 nM
|
|
|
|
CP0450725
|
2-[6-(6-fluoropyridin-3-yl)-1,3-benzothiazole-2-carbonyl]-5-[(sulfamoylamino)methyl]-1,3,4-oxadiazole
Show/Hide
|
C16H11FN6O4S2
|
2
|
| 1 |
IC50 = 30 nM
|
|
|
| 2 |
IC50 = 40 nM
|
|
|
|
CP0521629
|
US9169240, 16
Show/Hide
|
C27H28N4O4S
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0451352
|
US9493412, 34
Show/Hide
|
C21H22N2O4
|
1
|
| 1 |
IC50 = 32.12 nM
|
|
|
|
CP0957917
|
US9169240, 85
Show/Hide
|
C23H17N7O5S
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0413214
|
US9169240, 76
Show/Hide
|
C23H17N5O2S
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0556995
|
US9169240, 28
Show/Hide
|
C18H15N5O4S2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0480000
|
N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-1-methyl-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C15H16Cl2N2O3
|
2
|
| 1 |
IC50 = 41 nM
|
|
|
| 2 |
IC50 = 1760 nM
|
|
|
|
CP0553278
|
US9493412, 2
Show/Hide
|
C19H18N2O4
|
1
|
| 1 |
IC50 = 43.05 nM
|
|
|
|
CP0535938
|
US9493412, 218
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
IC50 = 43.54 nM
|
|
|
|
CP0565591
|
US9169240, 56
Show/Hide
|
C20H15N5O3S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0557005
|
US9169240, 59
Show/Hide
|
C24H17FN4O2S
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0515231
|
US9493412, 8
Show/Hide
|
C19H17FN2O4
|
1
|
| 1 |
IC50 = 49.45 nM
|
|
|
|
CP0458543
|
US9493412, 103
Show/Hide
|
C21H21N3O4
|
1
|
| 1 |
IC50 = 49.64 nM
|
|
|
|
CP0458544
|
US9493412, 146
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 49.99 nM
|
|
|
|
CP0557006
|
US9169240, 60
Show/Hide
|
C24H16F2N4O2S
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0457151
|
N-[3-(3,4-dichlorophenyl)propyl]-1-ethyl-5-oxo-4-(2-pyridin-4-ylethylamino)-2H-pyrrole-3-carboxamide
Show/Hide
|
C23H26Cl2N4O2
|
2
|
| 1 |
IC50 = 59 nM
|
|
|
| 2 |
IC50 = 5990 nM
|
|
|
|
CP0476808
|
2-(2-chlorophenyl)-N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-1-methyl-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C21H19Cl3N2O3
|
2
|
| 1 |
IC50 = 59 nM
|
|
|
| 2 |
IC50 = 5750 nM
|
|
|
|
CP0410982
|
N-[3-(3,4-dichlorophenyl)propyl]-3-hydroxy-1-methyl-2-oxopyridine-4-carboxamide
Show/Hide
|
C16H16Cl2N2O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0478307
|
US9169240, 22
Show/Hide
|
C23H22N4O4S
|
1
|
| 1 |
IC50 = 66 nM
|
|
|
|
CP0483067
|
US9169240, 46
Show/Hide
|
C28H19N5O5S
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
|
CP0429256
|
US9169240, 25
Show/Hide
|
C18H15N5O4S2
|
4
|
| 1 |
IC50 = 86 nM
|
|
|
| 2 |
IC50 = 90 nM
|
|
|
| 3 |
IC50 = 200 nM
|
|
|
| 4 |
IC50 = 2000 nM
|
|
|
|
CP0419303
|
US9169240, 72
Show/Hide
|
C18H15N5O4S2
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0466067
|
2-cyclopropyl-N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-1-methyl-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C18H20Cl2N2O3
|
2
|
| 1 |
IC50 = 88 nM
|
|
|
| 2 |
IC50 = 5290 nM
|
|
|
|
CP0410983
|
N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-1-[3-(methanesulfonamido)-3-oxopropyl]-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C18H21Cl2N3O6S
|
2
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
IC50 = 1050 nM
|
|
|
|
CP0556993
|
US9169240, 6
Show/Hide
|
C24H22N4O4S
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0517891
|
US9169240, 86
Show/Hide
|
C21H17N5O3S
|
1
|
| 1 |
IC50 = 101 nM
|
|
|
|
CP0570766
|
US9169240, 58
Show/Hide
|
C18H13N5O3S
|
1
|
| 1 |
IC50 = 104 nM
|
|
|
|
CP0518626
|
US9169240, 52
Show/Hide
|
C19H16N4O3S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0517886
|
US9169240, 48
Show/Hide
|
C28H18FN5O5S
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0483070
|
US9169240, 67
Show/Hide
|
C22H20N4O4S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0419302
|
US9169240, 61
Show/Hide
|
C24H23FN4O5S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0413213
|
US9169240, 74
Show/Hide
|
C21H19N5O3S
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0517888
|
US9169240, 73
Show/Hide
|
C23H17N5O2S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0410984
|
N-[3-(3,4-dichlorophenyl)propyl]-4-hydroxy-1-(2-morpholin-4-ylethyl)-5-oxo-2H-pyrrole-3-carboxamide
Show/Hide
|
C20H25Cl2N3O4
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0429274
|
US9169240, 26
Show/Hide
|
C18H15N5O4S2
|
4
|
| 1 |
IC50 = 200 nM
|
|
|
| 2 |
IC50 = 240 nM
|
|
|
| 3 |
IC50 = 3000 nM
|
|
|
| 4 |
IC50 = 10000 nM
|
|
|
|
CP0518627
|
US9169240, 62
Show/Hide
|
C25H19FN4O3S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0481104
|
US9493412, 85
Show/Hide
|
C22H23N3O4
|
1
|
| 1 |
IC50 = 241.3 nM
|
|
|
|
CP0468031
|
US9493412, 92
Show/Hide
|
C20H19FN2O3
|
1
|
| 1 |
IC50 = 245.8 nM
|
|
|
|
CP0554800
|
US9493412, 62
Show/Hide
|
C19H17ClN2O3
|
1
|
| 1 |
IC50 = 246.3 nM
|
|
|
|
CP0518503
|
US9493412, 63
Show/Hide
|
C19H17FN2O3
|
1
|
| 1 |
IC50 = 249.5 nM
|
|
|
|
CP0565730
|
US9493412, 168
Show/Hide
|
C21H25F3N2O3
|
1
|
| 1 |
IC50 = 252.1 nM
|
|
|
|
CP0498012
|
US9493412, 104
Show/Hide
|
C23H25N3O4
|
1
|
| 1 |
IC50 = 253.5 nM
|
|
|
|
CP0564131
|
US9493412, 83
Show/Hide
|
C21H23N3O5S
|
1
|
| 1 |
IC50 = 256.6 nM
|
|
|
|
CP0554799
|
US9493412, 22
Show/Hide
|
C18H22N2O5
|
1
|
| 1 |
IC50 = 270.4 nM
|
|
|
|
CP0561679
|
US9493412, 91
Show/Hide
|
C21H19F3N2O3
|
1
|
| 1 |
IC50 = 270.9 nM
|
|
|
|
CP0515232
|
US9493412, 96
Show/Hide
|
C21H19N3O3
|
1
|
| 1 |
IC50 = 277.3 nM
|
|
|
|
CP0398272
|
US9493412, 66
Show/Hide
|
C21H20N2O4
|
1
|
| 1 |
IC50 = 285 nM
|
|
|
|
CP0482705
|
US9169240, 66
Show/Hide
|
C19H13FN4O2S
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0483069
|
US9169240, 63
Show/Hide
|
C24H16F2N4O2S
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0480001
|
US9249096, 1
Show/Hide
|
C14H14Cl2N2O3
|
2
|
| 1 |
IC50 = 296 nM
|
|
|
| 2 |
IC50 = 527.8 nM
|
|
|
|
CP0517887
|
US9169240, 69
Show/Hide
|
C25H20N4O4S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0517889
|
US9169240, 79
Show/Hide
|
C26H20N4O2S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0561363
|
US9169240, 90
Show/Hide
|
C23H16N4O4S2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0575660
|
US8993557, 37
Show/Hide
|
C21H23F3N2O3
|
1
|
| 1 |
IC50 = 352 nM
|
|
|
|
CP0414561
|
US9249096, 208
Show/Hide
|
C15H16Cl2N2O3
|
1
|
| 1 |
IC50 = 384.1 nM
|
|
|
|
CP0557016
|
US9169240, 65
Show/Hide
|
C24H16ClFN4O2S
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0477851
|
US9249096, 17
Show/Hide
|
C19H24Cl2N2O3
|
1
|
| 1 |
IC50 = 430.2 nM
|
|
|
|
CP0545801
|
US9249096, 294
Show/Hide
|
C16H17F3N2O3
|
1
|
| 1 |
IC50 = 436 nM
|
|
|
|
CP0560975
|
US9169240, 80
Show/Hide
|
C26H20N4O2S
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0554802
|
US9493412, 214
Show/Hide
|
C21H22Cl2N4O3
|
1
|
| 1 |
IC50 = 460.4 nM
|
|
|
|
CP0511944
|
US8993557, 44
Show/Hide
|
C19H21ClN2O3
|
1
|
| 1 |
IC50 = 475.1 nM
|
|
|
|
CP0414560
|
US9249096, 193
Show/Hide
|
C23H23Cl2FN2O3
|
1
|
| 1 |
IC50 = 485.7 nM
|
|
|
|
CP0493387
|
US9249096, 192
Show/Hide
|
C22H20Cl2N2O5
|
1
|
| 1 |
IC50 = 487.7 nM
|
|
|
|
CP0429134
|
US9169240, 91
Show/Hide
|
C22H16F3N5O3S
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0561362
|
US9169240, 81
Show/Hide
|
C27H22N4O3S
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
|
CP0517904
|
US9169240, 88
Show/Hide
|
C27H20F3N5O2S
|
1
|
| 1 |
IC50 = 494 nM
|
|
|
|
CP0576449
|
US9249096, 195
Show/Hide
|
C23H24Cl2N2O3
|
1
|
| 1 |
IC50 = 523.5 nM
|
|
|
|
CP0414554
|
US9249096, 5
Show/Hide
|
C14H15ClN2O3
|
1
|
| 1 |
IC50 = 559.1 nM
|
|
|
|
CP0493386
|
US9249096, 30
Show/Hide
|
C23H24Cl2N2O3
|
1
|
| 1 |
IC50 = 583.6 nM
|
|
|
|
CP0464480
|
US8993557, 39
Show/Hide
|
C22H25F3N2O3
|
1
|
| 1 |
IC50 = 691.8 nM
|
|
|
|
CP0451055
|
US9249096, 3
Show/Hide
|
C14H16N2O3
|
2
|
| 1 |
IC50 = 2947 nM
|
|
|
| 2 |
IC50 = 2950 nM
|
|
|
|
CP0544402
|
US9249096, 235
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|
C21H20Cl2N2O3
|
1
|
| 1 |
IC50 = 3063 nM
|
|
|
|
CP0515233
|
US9493412, 179
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|
C28H32FN3O3
|
1
|
| 1 |
IC50 = 3094 nM
|
|
|
|
CP0577770
|
US9249096, 265
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|
C16H21N3O4
|
1
|
| 1 |
IC50 = 3461 nM
|
|
|
|
CP0577769
|
US9249096, 229
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|
C16H18Cl2N2O3
|
1
|
| 1 |
IC50 = 4549 nM
|
|
|
|
CP0562471
|
US8993557, 33
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|
C19H19F4N3O3
|
1
|
| 1 |
IC50 = 4571 nM
|
|
|
|
CP0520870
|
US9493412, 172
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|
C25H28N2O5S
|
1
|
| 1 |
IC50 = 4724 nM
|
|
|
|
CP0459907
|
US9493412, 157
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|
C19H21Cl2N3O4
|
1
|
| 1 |
IC50 = 4842 nM
|
|
|
|
CP0554801
|
US9493412, 181
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|
C21H29N3O3
|
1
|
| 1 |
IC50 = 5733 nM
|
|
|
|
CP0451054
|
US9249096, 166
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|
C15H18N2O3
|
2
|
| 1 |
IC50 = 5830 nM
|
|
|
| 2 |
IC50 = 6445 nM
|
|
|
|
CP0506965
|
US8993557, 31
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|
C18H21N3O3
|
1
|
| 1 |
IC50 = 6453 nM
|
|
|
|
CP0472807
|
US9139578, Reference 3
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|
C17H15FN6O3S2
|
1
|
| 1 |
IC50 = 6518 nM
|
|
|
|
CP0556075
|
US8993557, 29
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|
C19H23N3O3
|
1
|
| 1 |
IC50 = 6545 nM
|
|
|
|
CP0498015
|
US9493412, 210
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|
C26H31N3O3
|
1
|
| 1 |
IC50 = 6570 nM
|
|
|
|
CP0481105
|
US9493412, 169
Show/Hide
|
C21H23F5N2O3
|
1
|
| 1 |
IC50 = 7169 nM
|
|
|
|
CP0481108
|
US9493412, 196
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|
C22H27N3O4
|
1
|
| 1 |
IC50 = 8254 nM
|
|
|
|
CP0458579
|
US9493412, 212
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|
C21H26N2O3
|
1
|
| 1 |
IC50 = 8276 nM
|
|
|
|
CP0498013
|
US9493412, 173
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|
C17H20N2O3
|
1
|
| 1 |
IC50 = 8468 nM
|
|
|
|
CP0564130
|
US9493412, 24
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|
C19H23N3O4
|
1
|
| 1 |
IC50 = 9295 nM
|
|
|
|
CP0414562
|
US9249096, 230
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|
C18H22Cl2N2O3
|
1
|
| 1 |
IC50 = 9643 nM
|
|
|
|
CP0481106
|
US9493412, 178
Show/Hide
|
C24H28F3N3O4
|
1
|
| 1 |
IC50 = 9919 nM
|
|
|
|
CP0406780
|
US9139578, Reference 4
Show/Hide
|
C17H15FN6O4S2
|
1
|
| 1 |
IC50 = 14880 nM
|
|
|
