Brief Information of the Compound and Protein
Compound Name
US9139578, 22
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PubChem ID
CID: 72945014
Canonical SMILES
Fc1cc(cc2sc(nc12)C(NC(=O)c1ccc(cc1)C(F)(F)F)c1nnc(CC2SC(=O)NC2=O)o1)-c1ccccc1
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Compound Formula C28H17F4N5O4S2
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
IC50 < 10 nM
   TI
   LI
   LO
   TS