Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9169240, 91
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 PubChem ID
CID: 118322819
Canonical SMILES
FC(F)(F)CN1CCC(Nc2nnc(o2)C(=O)c2nc3ccc(cc3s2)-c2ccccc2)C1=O
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Compound Formula C22H16F3N5O3S
Compound Structure
Protein Name
 Protein Info 
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS