Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8754113, I-1-85
    Show/Hide
 PubChem ID
CID: 70800861
Canonical SMILES
NS(=O)(=O)NCc1nnc(Cc2nc3ccc(cc3s2)-c2ccccc2)o1
    Show/Hide
Compound Formula C17H15N5O3S2
Compound Structure
Protein Name
 Protein Info 
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 < 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM
2 IC50 = 6 nM