Brief Information of the Compound and Protein
Compound Name
US9169240, 27
    Show/Hide
PubChem ID
CID: 118322800
Canonical SMILES
CN(Cc1nnc(o1)C(=O)c1nc2ccc(cc2s1)-c1ccccc1)S(N)(=O)=O
    Show/Hide
Compound Formula C18H15N5O4S2
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  4
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 23 nM
   TI
   LI
   LO
   TS
3
IC50 = 1000 nM
   TI
   LI
   LO
   TS
4
IC50 = 7000 nM
   TI
   LI
   LO
   TS