Brief Information of the Compound and Protein
Compound Name
US9169240, 25
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PubChem ID
CID: 118322776
Canonical SMILES
C[C@@H](NS(N)(=O)=O)c1nnc(o1)C(=O)c1nc2ccc(cc2s1)-c1ccccc1
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Compound Formula C18H15N5O4S2
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  4
1
IC50 = 86 nM
   TI
   LI
   LO
   TS
2
IC50 = 90 nM
   TI
   LI
   LO
   TS
3
IC50 = 200 nM
   TI
   LI
   LO
   TS
4
IC50 = 2000 nM
   TI
   LI
   LO
   TS