Brief Information of the Compound and Protein
Compound Name
US9169240, 85
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PubChem ID
CID: 121231536
Canonical SMILES
O=C(c1nnc(N(Cc2n[nH]c(=O)o2)[C@H]2CCNC2=O)o1)c1nc2ccc(-c3ccccc3)cc2s1
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Compound Formula C23H17N7O5S
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS