Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9169240, 61
    Show/Hide
 PubChem ID
CID: 118322796
Canonical SMILES
COC(=O)[C@H](COC(C)(C)C)Nc1nnc(o1)C(=O)c1nc2ccc(cc2s1)-c1ccc(F)cc1
    Show/Hide
Compound Formula C24H23FN4O5S
Compound Structure
Protein Name
 Protein Info 
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS