Brief Information of the Compound and Protein
Compound Name
5-methyl-5-[[5-[methylsulfonyl-(6-phenyl-1,3-benzothiazol-2-yl)methyl]-1,3,4-oxadiazol-2-yl]methyl]imidazolidine-2,4-dione
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PubChem ID
CID: 72944930
Canonical SMILES
CC1(Cc2nnc(o2)C(c2nc3ccc(cc3s2)-c2ccccc2)S(C)(=O)=O)NC(=O)NC1=O
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Compound Formula C22H19N5O5S2
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  3
1
IC50 < 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 160 nM
   TI
   LI
   LO
   TS
3
IC50 = 380 nM
   TI
   LI
   LO
   TS