Brief Information of the Compound and Protein
Compound Name
4-[4-[2-[benzylsulfonyl-[5-[(sulfamoylamino)methyl]-1,3,4-oxadiazol-2-yl]methyl]-1,3-benzothiazol-6-yl]-2-chlorobenzoyl]morpholine
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PubChem ID
CID: 90082284
Canonical SMILES
NS(=O)(=O)NCc1nnc(o1)C(c1nc2ccc(cc2s1)-c1ccc(C(=O)N2CCOCC2)c(Cl)c1)S(=O)(=O)Cc1ccccc1
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Compound Formula C29H27ClN6O7S3
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  3
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 340 nM
   TI
   LI
   LO
   TS
3
IC50 = 4200 nM
   TI
   LI
   LO
   TS