Brief Information of the Compound and Protein
Compound Name
US9493412, 179
    Show/Hide
Canonical SMILES
OC1=C(CN(C2CCN(CC2)c2ccc(F)cc2)C1=O)C(=O)N[C@H]1CC[C@H](CC1)c1ccccc1
    Show/Hide
Compound Formula C28H32FN3O3
Compound Structure
Protein Name
Endothelial lipase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
Q9Y5X9
Gene Name
LIPG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
IC50 = 3094 nM
   TI
   LI
   LO
   TS