| Compound ID |
Compound Name |
Compound Formula |
|
CP0516556
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(1,3-thiazol-2-yl)cyclohexane-1-carboxamide
Show/Hide
|
C31H26FN7OS
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0157070
|
3-[8-amino-1-(4-methoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C27H25N5O2
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
IC50 = 320 nM
|
|
|
|
CP0469099
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(2-aminophenyl)cyclohexane-1-carboxamide
Show/Hide
|
C34H30FN7O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0243905
|
3-[8-amino-1-(8-fluoro-4-methoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C27H24FN5O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0305373
|
3-[8-amino-1-(4-ethoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C28H27N5O2
|
2
|
| 1 |
IC50 = 4 nM
|
|
|
| 2 |
IC50 = 440 nM
|
|
|
|
CP0505575
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyridin-2-ylcyclohexane-1-carboxamide
Show/Hide
|
C33H28FN7O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0516554
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-methylcyclohexane-1-carboxamide
Show/Hide
|
C29H27FN6O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0516555
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(1H-pyrazol-5-yl)cyclohexane-1-carboxamide
Show/Hide
|
C31H27FN8O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0533185
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(1,3,4-thiadiazol-2-yl)cyclohexane-1-carboxamide
Show/Hide
|
C30H25FN8OS
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0249970
|
3-[8-amino-1-(4-ethoxy-8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C28H26FN5O2
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0257954
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(1H-benzimidazol-2-yl)cyclohexane-1-carboxamide
Show/Hide
|
C35H29FN8O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0542032
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]cyclohexane-1-carboxamide
Show/Hide
|
C28H25FN6O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0516557
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-pyrimidin-4-ylcyclohexane-1-carboxamide
Show/Hide
|
C32H27FN8O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0532624
|
[4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]cyclohexyl]methanol
Show/Hide
|
C28H26FN5O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0543674
|
4-(3-(4-amino-5-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-7-yl)cyclobutyl)piperazine-1-carbaldehyde
Show/Hide
|
C29H27FN8O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0338451
|
3-[8-amino-1-(8-fluoro-4-phenoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C32H26FN5O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0302478
|
2-N-(3-methoxy-4-morpholin-4-ylphenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
|
C24H24N6O2
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0249103
|
1-(8-fluoro-4-methoxy-2-phenylquinolin-7-yl)-3-[3-(4-methylpiperazin-1-yl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C31H32FN7O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0347340
|
1-(4-ethoxy-8-fluoro-2-phenylquinolin-7-yl)-3-[3-(4-methylpiperazin-1-yl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C32H34FN7O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0153829
|
3-[8-amino-1-(2-phenyl-4-propan-2-yloxyquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C29H29N5O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0221803
|
3-[8-amino-1-(8-fluoro-2-phenyl-4-propan-2-yloxyquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C29H28FN5O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0469100
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(1-methylbenzimidazol-2-yl)cyclohexane-1-carboxamide
Show/Hide
|
C36H31FN8O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0465696
|
5-(8-fluoro-2-phenylquinolin-7-yl)-7-(3-(4-methylpiperazin-1-yl)cyclobutyl)imidazo[1,5-f][1,2,4]triazin-4-amine
Show/Hide
|
C29H29FN8
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0494373
|
4-N-isoquinolin-3-yl-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
|
C22H21N5O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0243904
|
1-(4-methoxy-2-phenylquinolin-7-yl)-3-[3-(4-methylpiperazin-1-yl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C31H33N7O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0178235
|
3-[3-(morpholin-4-ylmethyl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C30H30N6O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0162376
|
3-[4-amino-5-(8-fluoro-2-phenylquinolin-7-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C25H21FN6O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0288445
|
3-(3-morpholin-4-ylcyclobutyl)-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C29H28N6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0288446
|
3-[3-(morpholin-4-ylmethyl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C30H30N6O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0195241
|
3-[3-[(dimethylamino)methyl]cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C28H28N6
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0378284
|
3-((1s,3s)-3-(4-methylpiperazin-1-yl)cyclobutyl)-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C30H31N7
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0142928
|
4-N-quinolin-3-yl-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
|
C22H21N5O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0037781
|
3-[3-(azetidin-1-ylmethyl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C29H28N6
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0379423
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(1H-1,2,4-triazol-5-yl)cyclohexane-1-carboxamide
Show/Hide
|
C30H26FN9O
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0038512
|
3-[3-[(dimethylamino)methyl]cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C28H28N6
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0508825
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N-(1H-indol-5-yl)cyclohexane-1-carboxamide
Show/Hide
|
C36H30FN7O
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0040803
|
N-(2,6-difluorophenyl)-5-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]-2-methoxybenzamide
Show/Hide
|
C44H47F2N9O5S
|
2
|
| 1 |
IC50 = 22 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0243906
|
3-[8-amino-1-(4-phenoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
Show/Hide
|
C32H27N5O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0095983
|
(1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol
Show/Hide
|
C26H23N5O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0199081
|
1-(4-ethoxy-2-phenylquinolin-7-yl)-3-[3-(4-methylpiperazin-1-yl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C32H35N7O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0487314
|
7-(3-(4-methylpiperazin-1-yl)cyclobutyl)-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-4-amine
Show/Hide
|
C29H30N8
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0503936
|
4-(3-(4-amino-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-7-yl)cyclobutyl)piperazine-1-carbaldehyde
Show/Hide
|
C29H28N8O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0286005
|
1-(8-fluoro-2-phenyl-4-propan-2-yloxyquinolin-7-yl)-3-[3-(4-methylpiperazin-1-yl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C33H36FN7O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0533308
|
4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-N,N-dimethylcyclohexane-1-carboxamide
Show/Hide
|
C30H29FN6O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0509038
|
N-(2,6-difluorophenyl)-3-[3-[2-[2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C41H41F2N9O2
|
2
|
| 1 |
IC50 = 28 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0223818
|
3-[3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenyl-4-propan-2-yloxyquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C33H37N7O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0069911
|
N-(2,6-difluorophenyl)-3-[3-[2-[2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C41H41F2N9O4S
|
2
|
| 1 |
IC50 = 36 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0338075
|
2-N-[3-methoxy-4-(3-piperidin-1-ylpropoxy)phenyl]-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
|
C28H32N6O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0441568
|
4-N-quinolin-6-yl-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
|
C22H21N5O3
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0040804
|
3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)-2-methoxyphenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C41H40F2N8O2
|
2
|
| 1 |
IC50 = 38 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0475298
|
N-(2,6-difluorophenyl)-3-[3-[2-[2-methoxy-4-(4-pyrrolidin-1-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C40H38F2N8O2
|
2
|
| 1 |
IC50 = 38 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0380415
|
(R)-N-(2,6-difluorophenyl)-3-(3-(2-(4-(4-(3-fluoropyrrolidin-1-yl)piperidin-1-yl)-2-methoxyphenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C40H37F3N8O2
|
2
|
| 1 |
IC50 = 40 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0444853
|
N-(2,6-difluorophenyl)-3-[3-[2-[2-methoxy-4-(4-morpholin-4-ylpiperidin-1-yl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C40H38F2N8O3
|
2
|
| 1 |
IC50 = 41 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0228941
|
3-[3-(azetidin-1-ylmethyl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C29H28N6
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0203365
|
1-(2-phenylquinolin-7-yl)-3-(3-piperidin-1-ylcyclobutyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C30H30N6
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0461636
|
3-(3-(2-(4-(4-(4-acetylpiperazin-1-yl)piperidin-1-yl)-2-methoxyphenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C42H41F2N9O3
|
2
|
| 1 |
IC50 = 65 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0388757
|
N-(2,6-difluorophenyl)-3-[3-[2-[4-[4-[(2R,6S)-2,6-dimethylmorpholin-4-yl]piperidin-1-yl]-2-methoxyanilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C42H42F2N8O3
|
2
|
| 1 |
IC50 = 68 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0514452
|
N,N-dimethyl-3-[3-[3-[(2-phenoxyphenyl)carbamoylamino]phenyl]-1H-pyrrolo[2,3-b]pyridin-5-yl]benzamide
Show/Hide
|
C35H29N5O3
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0180038
|
1-(8-fluoro-4-phenoxy-2-phenylquinolin-7-yl)-3-[3-(4-methylpiperazin-1-yl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C36H34FN7O
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0339944
|
CHEMBL261146
Show/Hide
|
C29H28N6
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
|
CP0137584
|
2-N-[4-(3-piperidin-1-ylpropoxy)phenyl]-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
|
C27H30N6O
|
1
|
| 1 |
IC50 = 81 nM
|
|
|
|
CP0085420
|
3-cyclobutyl-1-(2-phenylquinolin-7-yl)-imidazo[1,5-a]pyrazin-8-ylamine
Show/Hide
|
C25H21N5
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0177146
|
3-(3-(2-(4-(1,4'-bipiperidin-1'-yl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C40H38F2N8O
|
2
|
| 1 |
IC50 = 87 nM
|
|
|
| 2 |
IC50 < 100 nM
|
|
|
|
CP0206887
|
4-N-naphthalen-2-yl-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
|
C23H22N4O3
|
1
|
| 1 |
IC50 = 88 nM
|
|
|
|
CP0042282
|
N-(2,6-difluorophenyl)-3-[3-[2-[5-ethyl-2-methoxy-4-[4-(4-methylsulfonylpiperazin-1-yl)piperidin-1-yl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C43H45F2N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0461635
|
N-(2,6-difluorophenyl)-3-[3-[2-[3-[2-(dimethylamino)ethoxy]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C34H29F2N7O2
|
2
|
| 1 |
IC50 = 100 nM
|
|
|
| 2 |
IC50 = 177 nM
|
|
|
|
CP0845764
|
3-[3-(2-{[4-(1,4'-bipiperidin-l'-yl)-2-methylphenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C41H40F2N8O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0845773
|
N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[4-(4-thiomorpholinyl)-1-piperidinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C40H38F2N8O2S
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1
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| 1 |
IC50 = 100 nM
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CP0845774
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
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C43H43F2N9O3
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1
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| 1 |
IC50 < 100 nM
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CP0845775
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[1-(2-fluoroethyl)-4-piperidinyl]-1-piperazinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H42F3N9O2
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1
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| 1 |
IC50 < 100 nM
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CP0845776
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(cis-4-{4-[2-(methylsulfonyl)-ethyl]-1-piperazinyl}cyclohexyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C44H46F2N8O4S
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1
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| 1 |
IC50 < 100 nM
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CP0845777
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(2-(methyloxy)-4-{1'-[2-(methylsulfonyl)ethyl]-4,4'-bipiperidin-1-yl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C45H48F2N8O5S
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1
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| 1 |
IC50 < 100 nM
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CP0845778
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2,5-bis(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C42H42F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0845779
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(ethyloxy)-4-(4-{4-[2-(methylsulfonyl)ethyl]-1-piperazin-yl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C44H47F2N9O4S
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1
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| 1 |
IC50 < 100 nM
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CP0845780
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N-(2,6-difluorophenyl)-3-{3-[2-({4-(4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}-1-piperidinyl)-2-[(2,2,2-trifluoroethyl)oxy]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C44H44F5N9O4S
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1
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| 1 |
IC50 < 100 nM
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CP0845781
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N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[4-(methyloxy)-1-piperidinyl]phenyl}-amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C37H33F2N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0845782
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N-(2,6-difluorophenyl)-5-[3-(2-{[2-(ethyloxy)-4-(4-propyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
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C40H40F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0845783
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-[3-(2-{[2-(ethyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H43F2N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0845802
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N-(2,6-difluorophenyl)-3-(3-{2-[(2-(methyloxy)-4-{1'-[2-(methylsulfonyl)ethyl]-4,4'-bipiperidin-1-yl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C44H46F2N8O4S
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1
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| 1 |
IC50 < 100 nM
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CP0845803
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N-(2,6-difluorophenyl)-3-(3-{2-[(2-(methyloxy)-4-{1'-[2-(methylsulfonyl)ethyl]-1,4'-bipiperidin-4-yl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C44H46F2N8O4S
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1
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| 1 |
IC50 < 100 nM
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CP0845804
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N-(2,6-difluorophenyl)-3-(3-(2-((2-(methyloxy)-4-(4-(2-(methylsulfonyl)ethyl)-1,4'-bipiperidin-1'-yl)phenyl)amino)-4-pyrimidinyl)imidazo(1,2-a)pyridin-2-yl)benzamide
Show/Hide
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C44H46F2N8O4S
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1
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| 1 |
IC50 < 100 nM
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CP0845805
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-5-chloro-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C41H39ClF2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0845806
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-5-methyl-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C42H42F2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0845807
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2,5-bis(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H44F3N9O3
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1
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| 1 |
IC50 < 100 nM
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CP0845808
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N-(2,6-difluorophenyl)-5-{3-[2-({5-fluoro-2-(methyloxy)-4-[2-(1-piperidinyl)ethyl]phenyl}-amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
Show/Hide
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C39H36F3N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0845809
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3-{3-[2-({5-fluoro-2-(methyloxy)-4-[2-(1-piperidinyl)ethyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-N-(2,4,6-trifluorophenyl)benzamide
Show/Hide
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C38H33F4N7O2
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1
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| 1 |
IC50 = 100 nM
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CP0845810
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-{3-[2-({2-(methyloxy)-4-[2-(4-methyl-1-piperazinyl)ethyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C40H40F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0845836
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N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[3-(1-piperidinyl)propyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C39H37F2N7O2
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1
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| 1 |
IC50 < 100 nM
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CP0845845
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C43H45F2N9O5S
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1
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| 1 |
IC50 < 100 nM
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CP0845847
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3-[3-(2-{[4-(1,4'-bipiperidin-l'-yl)-2-(ethyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C42H42F2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0845849
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N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[4-(1-piperidinylmethyl)-1-piperidinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C42H42F2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0845866
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N-(2,6-difluorophenyl)-2-[(1-methylethyl)oxy]-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C43H45F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0848311
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[2-(methyloxy)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C40H40F2N8O4
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1
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| 1 |
IC50 < 100 nM
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CP0848312
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[(3S)-3-fluoro-1-pyrrolidinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C40H37F3N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0848316
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[(3R)-3-hydroxy-1-piperidinyl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C36H31F2N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0848317
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N-(2,6-difluorophenyl)-3-(3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C39H37F2N7O4S
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1
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| 1 |
IC50 = 100 nM
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CP0848319
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N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C43H45F2N9O5S
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1
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| 1 |
IC50 < 100 nM
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CP0848470
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-7-(methyloxy)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H44F3N9O3
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1
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| 1 |
IC50 < 100 nM
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CP0848471
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N-(2,6-difluorophenyl)-5-[3-(2-{[4-[4-(l-methylethyl)-1-piperazinyl]-2-(methyloxy)phenyl]-amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
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C39H38F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0848472
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N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-[(1-methylethyl)oxy]benzamide
Show/Hide
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C43H45F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0848486
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-[3-(2-{[5-methyl-2-(methyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H43F2N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0848487
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(ethyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(ethyloxy)benzamide
Show/Hide
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C44H47F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0848489
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N-(2,6-difluorophenyl)-3-(3-(2-(2-methyl-4-(1-methylpiperidin-4-yloxy)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C37H33F2N7O2
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1
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| 1 |
IC50 < 100 nM
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CP0848526
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-(4-methyl-1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H42F2N8O2
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1
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| 1 |
IC50 = 100 nM
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CP0848527
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5-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-3-methyl-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(ethyloxy)benzamide
Show/Hide
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C44H46F2N8O3
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1
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| 1 |
IC50 = 100 nM
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CP0848528
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H42F3N9O2
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1
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| 1 |
IC50 < 100 nM
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CP0848529
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-[3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C44H46F3N9O3
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1
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| 1 |
IC50 < 100 nM
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CP0848530
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-(4-hydroxy-1,4'-bipiperidin-1'-yl)-2-(methyloxy)-phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C41H40F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0848531
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[1'-(2-fluoroethyl)-4,4'-bipiperidin-1-yl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H43F3N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0848532
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N-(2,6-difluorophenyl)-3-[3-(2-{[5-methyl-2-(methyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C40H39F2N7O2
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1
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| 1 |
IC50 < 100 nM
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CP0848534
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(ethyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(ethyloxy)benzamide
Show/Hide
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C43H46F2N8O5S
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1
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| 1 |
IC50 < 100 nM
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CP0848538
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-methyl-4-(4-piperidinyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C36H31F2N7O2
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1
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| 1 |
IC50 = 100 nM
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CP0848539
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N-(2,3-difluorophenyl)-3-[3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}-7-(methyloxy)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C35H31F2N7O3
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1
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| 1 |
IC50 = 100 nM
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CP0856490
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3-{3-[2-({4-(1,4'-bipiperidin-1'-yl)-2-[(1-methylethyl)oxy]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C43H44F2N8O2
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1
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| 1 |
IC50 = 100 nM
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CP0856492
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-8-methylimidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C42H42F2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0856495
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C38H34F2N8O3
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1
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| 1 |
IC50 = 100 nM
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CP0856496
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidin}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-7-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H41F6N9O2
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1
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| 1 |
IC50 = 100 nM
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CP0856497
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N-(2,6-difluorophenyl)-3-(7-fluoro-3-(2-((2-(methyloxy)-4-(4-(4-(methylsulfonyl)-1-piperazinyl)-1-piperidinyl)phenyl)amino)-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C41H40F3N9O4S
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1
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| 1 |
IC50 < 100 nM
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CP0856498
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5-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-7-fluoroimidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
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C42H41F3N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0856500
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N-(2,6-difluorophenyl)-5-{3-[2-({5-methyl-2-(methyloxy)-4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
Show/Hide
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C39H38F2N8O5S
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1
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| 1 |
IC50 < 100 nM
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CP0856509
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}-2-propylphenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C43H45F2N7O4S
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1
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| 1 |
IC50 < 100 nM
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CP0856510
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C41H42F2N8O5S
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1
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| 1 |
IC50 < 100 nM
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CP0856511
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-8-fluoroimidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C41H39F3N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0856513
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]hexahydro-1H-1,4-diazepin-1-yl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C42H44F2N8O5S
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1
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| 1 |
IC50 < 100 nM
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CP0857311
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C40H40F2N8O5S
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1
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| 1 |
IC50 < 100 nM
|
|
|
|
CP0857313
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C42H43F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857314
|
N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(ethyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C45H49F2N9O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857315
|
N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(ethyloxy)benzamide
Show/Hide
|
C43H45F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857317
|
N-(2,6-difluorophenyl)-2-(methyloxy)-5-{3-[2-({2-(methyloxy)-4-[3-(1-piperidinyl)propyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C40H39F2N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857318
|
N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[3-(4-methyl-1-piperazinyl)propyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C39H38F2N8O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0857321
|
N-(2,6-difluorophenyl)-3-(3-{2-[(5-methyl-2-(methyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C40H39F2N7O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857322
|
N-(2,6-difluorophenyl)-2-(methyloxy)-5-[3-(2-{[2-(methyloxy)-4-(4-propyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C39H38F2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857323
|
N-(2,6-difluorophenyl)-3-[8-fluoro-3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C42H41F4N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857324
|
N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(ethyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(ethyloxy)benzamide
Show/Hide
|
C46H51F2N9O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857326
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(ethyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C44H47F2N9O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857327
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C42H43F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0857328
|
N-(2,6-difluorophenyl)-2-((1-methylethyl)oxy)-5-(3-(2-((2-(methyloxy)-4-(4-(4-(methylsulfonyl)-1-piperazinyl)-1-piperidinyl)phenyl)amino)-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C44H47F2N9O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0861201
|
N-(2,6-difluorophenyl)-5-[3-(2-{[4-{(3S)-3-(1-methylethyl)-4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C42H44F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0861239
|
N-(2,6-difluorophenyl)-3-[3-(2-{[4-[1'-(2-fluoroethyl)-1,4'-bipiperidin-4-yl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C43H43F3N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0861240
|
N-(2,6-difluorophenyl)-5-[3-(2-{[4-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)-benzamide
Show/Hide
|
C39H36F2N8O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0861241
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C40H39F2N7O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0861242
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C40H40F2N8O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0863036
|
N-(2,6-difluorophenyL)-3-[8-methyl-3-(2-{[2-(methyloxy)-4-(4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C44H47F2N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0863038
|
N-(2,6-difluorophenyl)-5-{3-[2-({2-methyl-3-[(4-methyl-1-piperazinyl)methyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
Show/Hide
|
C38H36F2N8O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0863042
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{4-[1-(2-fluoroethyl)-4-piperidinyl]-1-piperazinyl]phenyl)amino}-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C43H44F3N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866109
|
N-(2,6-difluorophenyl)-5-(7-fluoro-3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C40H38F3N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866110
|
N-(2,6-difluorophenyl)-5-[3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}-7-(methyloxy)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C36H33F2N7O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866111
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C38H36F2N8O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866112
|
N-(2,6-difluorophenyl)-3-{3-[2-({5-methyl-2-(methyloxy)-4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C37H34F2N8O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866113
|
N-(2,6-difluorophenyl)-3-(3-(2-((5-methyl-2-(methyloxy)-4-(4-(2-(methylsulfonyl)ethyl)-1-piperidinyl)phenyl)amino)-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C40H39F2N7O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866114
|
N-(2,6-difluorophenyl)-2-(methyloxy)-5-{3-[2-({2-(methyloxy)-4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C37H34F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866115
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methyloxy)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C41H42F2N8O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866116
|
3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-7-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C42H39F5N8O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866958
|
N-(2,6-difluorophenyl)-3-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C42H43F2N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866959
|
N-(2,6-difluorophenyl)-3-[3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}-7-(methyloxy)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C35H31F2N7O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866960
|
3-[3-(2-{[4-(4-{bis[2-(methyloxy)ethyl]amino}-1-piperidinyl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C42H44F2N8O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866983
|
N-(2,6-difluorophenyl)-3-[3-(2-{[5-methyl-2-(methyloxy)-4-(4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C44H47F2N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866984
|
3-[3-(2-{[4-{4-[4-(2,2-difluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(ethyloxy)phenyl]-amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C43H43F4N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866985
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{4-[4-(3,3,3-trifluoropropyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C44H44F5N9O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866986
|
N-(2,6-difluorophenyl)-5-[3-(2-{[4-(4-hydroxy-1-piperidinyl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C37H33F2N7O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866987
|
N-(2,6-difluorophenyl)-3-{3-[2-({5-fluoro-2-(methyloxy)-4-[2-(1-piperidinyl)ethyl]phenyl}-amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C38H34F3N7O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866988
|
N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C40H40F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866989
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(ethyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C41H42F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866990
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C39H38F2N8O4S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0866991
|
N-(2,6-difluorophenyl)-3-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C39H38F2N8O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866992
|
N-(2,6-difluorophenyl)-3-(3-(2-((2-(ethyloxy)-4-(4-(1-methylethyl)-1-piperazinyl)phenyl)amino)-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C39H38F2N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866994
|
N-(2,6-difluorophenyl)-3-(8-fluoro-3-{2-[(2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C41H40F3N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866995
|
N-(2,6-difluorophenyl)-3-[7-fluoro-3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C42H41F4N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866996
|
5-(3-{2-[(5-chloro-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
|
C39H37ClF2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0866997
|
N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C42H43F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0867011
|
5-(3-(2-(4-(1,4'-bipiperidin-1'-yl)-2-methoxyphenylamino)pyrimidin-4-yl)-7-methoxyimidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide
Show/Hide
|
C43H44F2N8O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0867154
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C42H44F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0867164
|
3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(propyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyri-din-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C43H44F2N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0867165
|
N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C43H45F2N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0867166
|
3-[3-(2-{[5-chloro-4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C42H41ClF3N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869257
|
N-(2,6-difluorophenyl)-2-(methyloxy)-5-[3-(2-{[2-(methyloxy)-4-(4-{4-[2-(methylsulfonyl)-ethyl]-1-piperazinyl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo-[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C44H47F2N9O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0869420
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C41H42F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0870269
|
N-(2,6-difluorophenyl)-3-(3-(2-(3-(1-methyl-1H-pyrazol-4-yl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C34H24F2N8O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0870972
|
N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C42H43F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0870973
|
N-(2,6-difluorophenyl)-5-(7-fluoro-3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C41H40F3N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0870974
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C41H41F2N7O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0870978
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-[3-(2-{[2-(methyloxy)-4-(4-propyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C40H40F2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0870979
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(ethyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C42H43F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0870980
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(ethyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C43H45F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0870981
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C43H45F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0870983
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C41H41F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0871077
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5-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-5-fluoro-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
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C42H41F3N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0871078
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methyloxy)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C40H40F2N8O4
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1
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| 1 |
IC50 < 100 nM
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CP0873426
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-5-fluoro-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C41H39F3N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0873427
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N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[1-(2-methylpropyl)-4-piperidinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C40H39F2N7O2
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1
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| 1 |
IC50 < 100 nM
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CP0873428
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[(3S)-3-hydroxyl-piperidinyl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C36H31F2N7O3
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1
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| 1 |
IC50 = 100 nM
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CP0873429
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N-(2,6-difluorophenyl)-5-[3-(2-{[4-[1-(2-fluoroethyl)-4-piperidinyl]-2-(methyloxy)phenyl]-amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
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C39H36F3N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0873430
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C43H45F2N9O5S
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1
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| 1 |
IC50 < 100 nM
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CP0873431
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-7-(methyloxy)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C42H42F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0873432
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(2-methylpropyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C44H46F2N8O
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1
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| 1 |
IC50 < 100 nM
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CP0873433
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[4-(hexahydro-1H-azepin-1-yl)-1-piperidinyl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H42F2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0873434
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N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[4-(trifluoromethyl)-1,4'-bipiperidin-1'-yl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C42H39F5N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0873436
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[4-(4-ethyl-1-piperazinyl)-1-piperidinyl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H43F2N9O2
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1
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| 1 |
IC50 = 100 nM
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CP0873438
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C42H43F2N9O5S
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1
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| 1 |
IC50 < 100 nM
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CP0873679
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N-(2,6-difluorophenyl)-3-(3-{2-[(2-(methyloxy)-4-{4-[2-(methyloxy)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C38H36F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0873682
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-{3-[2-({2-(methyloxy)-4-[4-(methyloxy)-1-piperidinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C38H35F2N7O4
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1
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| 1 |
IC50 < 100 nM
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CP0873683
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[4-(2-fluoroethyl)-3-oxo-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C42H40F3N9O3
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1
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| 1 |
IC50 < 100 nM
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CP0873684
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C39H37F2N7O2
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1
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| 1 |
IC50 < 100 nM
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CP0873685
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N-(2,6-difluorophenyl)-3-{3-[2-({2-(ethyloxy)-4-[2-(4-methyl-1-piperazinyl)ethyl]-phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C37H34F2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0882930
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-[3-(2-{[2-(methyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C40H39F2N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0882931
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N-(2,6-difluorophenyl)-5-[3-(2-{[2-(ethyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
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C41H41F2N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0883050
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5-[3-(2-{[5-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
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C42H42F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0883053
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(4-chloro-2-fluorophenyl)benzamide
Show/Hide
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C41H40ClFN8O2
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1
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| 1 |
IC50 < 100 nM
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CP0883055
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-{3-[2-({2-(methyloxy)-4-[1-(2-methylpropyl)-4-piperidinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C41H41F2N7O3
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1
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| 1 |
IC50 < 100 nM
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CP0883056
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-[3-(2-{[4-[4-(1-methylethyl)-1-piperazinyl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C40H40F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0883073
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[4-(2-fluoro-ethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-8-methylimidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H44F3N9O2
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1
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| 1 |
IC50 < 100 nM
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CP0883074
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-[3-(2-{[2-(methyloxy)-4-(4-{4-[2-(methylsulfonyl)-ethyl]-1-piperazinyl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C45H49F2N9O5S
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1
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| 1 |
IC50 < 100 nM
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CP0883075
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N-(2,6-difluorophenyl)-5-[3-(2-{[4-{4-[(9aS)-hexahydropyrazino[2,1-c][1,4]oxazin-8(1H)-yl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
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C44H45F2N9O4
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1
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| 1 |
IC50 < 100 nM
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CP0888258
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[2-(methyloxy)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C39H38F2N8O4
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1
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| 1 |
IC50 < 100 nM
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CP0888352
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N-(2,6-difluorophenyl)-3-[8-fluoro-3-(2-{[2-(methyloxy)-4-(4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H44F3N9O4S
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1
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| 1 |
IC50 < 100 nM
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CP0888354
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N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-[(1-methylethyl)oxy]benzamide
Show/Hide
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C44H47F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0888370
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N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-[(1-methylethyl)oxy]benzamide
Show/Hide
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C43H46F2N8O5S
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1
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| 1 |
IC50 < 100 nM
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CP0888393
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5-(3-(2-(4-(1,4'-bipiperidin-1'-yl)-2-methoxyphenylamino)pyrimidin-4-yl)-7-methylimidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-methoxybenzamide
Show/Hide
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C43H44F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0888395
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-propylphenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C43H44F2N8O
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1
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| 1 |
IC50 < 100 nM
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CP0894025
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N-(2,6-difluorophenyl)-3-(8-methyl-3-{2-[(2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C42H43F2N9O4S
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1
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| 1 |
IC50 = 100 nM
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CP0894026
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[(3S)-3-hydroxy-1,4'-bipiperidin-1'-yl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C41H40F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0895685
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N-(2,6-difluorophenyl)-3-(3-(2-(2-methyl-4-(1-(2-(methylsulfonyl)ethyl)piperidin-4-yloxy)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C39H37F2N7O4S
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1
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| 1 |
IC50 < 100 nM
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CP0895686
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[(1S,4S)-5-(2-fluoroethyl)-2,5-diazabicyclo-[2.2.1]hept-2-yl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H42F3N9O2
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1
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| 1 |
IC50 < 100 nM
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CP0895687
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1,4'-bipiperidin-1'-yl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C45H48F2N8O5S
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1
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| 1 |
IC50 < 100 nM
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CP0895688
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N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C43H44F3N9O2
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1
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| 1 |
IC50 < 100 nM
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CP0895690
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(4-propyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C38H36F2N8O2
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1
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| 1 |
IC50 < 100 nM
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CP0895691
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N-(2,6-difluorophenyl)-5-[7-fluoro-3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
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C43H43F4N9O3
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1
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| 1 |
IC50 < 100 nM
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CP0895692
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(ethyloxy)benzamide
Show/Hide
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C45H49F2N9O5S
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1
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| 1 |
IC50 < 100 nM
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CP0895693
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N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C42H43F2N9O4S
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1
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| 1 |
IC50 < 100 nM
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CP0899488
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(methyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C41H41F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0899576
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N-(2,4-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C34H29F2N7O2
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1
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| 1 |
IC50 < 100 nM
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CP0899577
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N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[5-(1-pyrrolidinylmethyl)-1,3,4-oxadiazol-2-yl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C38H31F2N9O3
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1
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| 1 |
IC50 = 100 nM
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CP0899726
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C40H39F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0899730
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5-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
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C42H42F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0899732
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N-(2,6-difluorophenyl)-3-(3-{2-[(4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}-2-propylphenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C41H41F2N7O3S
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1
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| 1 |
IC50 < 100 nM
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CP0901852
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N-(2,6-difluorophenyl)-3-(3-{2-[(2-(methyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C39H37F2N7O4S
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1
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| 1 |
IC50 < 100 nM
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CP0901853
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N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C41H41F2N7O5S
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1
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| 1 |
IC50 < 100 nM
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CP0902860
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3-[3-(2-{[5-chloro-2-(methyloxy)-4-(4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-benzamide
Show/Hide
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C43H44ClF2N9O4S
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1
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| 1 |
IC50 < 100 nM
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CP0902861
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-{3-[2-({2-(methyloxy)-4-[2-(4-methyl-1-piperazinyl)ethyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C39H38F2N8O3
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1
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| 1 |
IC50 < 100 nM
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CP0904970
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(ethyloxy)-4-(1-propyl-4-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C40H39F2N7O2
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1
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| 1 |
IC50 < 100 nM
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CP0904973
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N-(2,6-difluorophenyl)-5-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)-amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C35H31F2N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0904974
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3-(3-(2-(3-(2-(dimethylamino)ethoxy)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2-fluoro-5-(trifluoromethyl)phenyl)benzamide
Show/Hide
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C35H29F4N7O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
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CP0904975
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-(4-hydroxy-1-piperidinyl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C36H31F2N7O3
|
1
|
| 1 |
IC50 < 100 nM
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|
|
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CP0904977
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3-[3-(2-{[4-(3,3-difluoro-1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C41H38F4N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0904979
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N-(2,6-difluorophenyl)-3-(3-{2-[(5-methyl-2-(methyloxy)-4-{4-[2-(methyloxy)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C39H38F2N8O3
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1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0904980
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N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
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C41H42F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0912085
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(trans-4-{4-[2-(methylsulfonyl)-ethyl]-1-piperazinyl}cyclohexyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C44H46F2N8O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0912086
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-{3-[2-({2-(methyloxy)-4-[3-(4-methyl-1-piperazinyl)propyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
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C40H40F2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0912113
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-7-methylimidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C42H42F2N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0912114
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}-1-piperidinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C43H45F2N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
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CP0912115
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N-(2,6-difluorophenyl)-3-[3-(2-{[2-(methyloxy)-4-(4-morpholinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C35H29F2N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0912117
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-5-methyl-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C43H44F3N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913017
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N-(2,6-difluorophenyl)-3-(3-(2-(2-methoxy-4-(4-(4-methyl-1,4-diazepan-1-yl)piperidin-1-yl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C42H43F2N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913018
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N-(2,6-difluorophenyl)-3-[3-(2-{[4-[4-(dimethylamino)-1-piperidinyl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C38H36F2N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913019
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N-(2,6-difluorophenyl)-5-[3-(2-{[4-[(3S)-3-hydroxy-1,4'-bipiperidin-1'-yl]-2-(methyloxy)-phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
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C42H42F2N8O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913020
|
N-(2,6-difluorophenyl)-3-[3-(2-{[2-(ethyloxy)-4-(4-propyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C39H38F2N8O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0913021
|
N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl]-2-propylphenyl)amino}-4-pyrimidinyl}imidazo[1,2a]pyridin-2-yl)benzamide
Show/Hide
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C42H43F2N7O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913022
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N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(2-(methyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C40H39F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913023
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N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(ethyloxy)benzamide
Show/Hide
|
C42H44F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913162
|
5-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-5-methyl-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
|
C43H44F2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913163
|
3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)-7-fluoroimidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C41H39F3N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913164
|
N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-5-methyl-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}-7-fluoroimidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C42H42F3N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913166
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-{3-[2-({2-(methyloxy)-4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C38H36F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913167
|
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(methyloxy)-4-{4-[(4-methyl-1-piperazinyl)methyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C42H43F2N9O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0913168
|
5-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-3-methyl-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
|
C43H44F2N8O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0914898
|
N-(2,6-difluorophenyl)-3-[3-(2-{[4-[4-(1-methylethyl)-1-piperazinyl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C38H36F2N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0919429
|
N-(2,6-difluorophenyl)-5-(3-{2-[(5-methyl-2-(methyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C41H41F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0919430
|
N-(2,6-difluorophenyl)-5-(7-fluoro-3-{2-[(2-(methyloxy)-4-{4-[4-(methylsulfonyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C42H42F3N9O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0919431
|
N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[4-(methylsulfonyl)-1-piperazinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C36H32F2N8O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0920901
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-{3-[2-({2-(methyloxy)-4-[1-(2-methylpropyl)-4-piperidinyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C42H43F2N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0921732
|
N-(2,6-difluorophenyl)-3-(3-(2-(2-methyl-3-((4-methylpiperazin-1-yl)methyl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C37H34F2N8O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0921734
|
N-(2,6-difluorophenyl)-5-{3-[2-({2-(ethyloxy)-4-[4-(1-methylethyl)-1-piperazinyl]phenyl}-amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
Show/Hide
|
C40H40F2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0921735
|
N-(2,6-difluorophenyl)-5-(3-{2-[(2-(ethyloxy)-4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}-phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
Show/Hide
|
C41H41F2N7O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0921758
|
3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,4-difluorophenyl)benzamide
Show/Hide
|
C41H40F2N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0921759
|
N-(2,6-difluorophenyl)-5-[3-(2-{[4-(4-hydroxy-1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]-amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C42H42F2N8O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0923164
|
N-(2,6-difluorophenyl)-5-[3-(2-{[4-{5-[(dimethylamino)methyl]-1,3,4-oxadiazol-2-yl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C37H31F2N9O4
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0923165
|
N-(2,6-difluorophenyl)-3-[3-(2-{[4-(4-fluoro-1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C41H39F3N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0924021
|
N-(5-chloro-2-fluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C34H29ClFN7O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0924036
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-[3-(2-{[2-(ethyloxy)-4-(4-propyl-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C41H42F2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0926153
|
3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2-chloro-4-fluorophenyl)benzamide
Show/Hide
|
C41H40ClFN8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0926162
|
N-(2,6-difluorophenyl)-2-(ethyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1,4'-bipiperidin-1'-yl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C46H50F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0926163
|
5-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-5-chloro-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)-2-(methyloxy)benzamide
Show/Hide
|
C42H41ClF2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0926165
|
3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-N-(2,4,6-trifluorophenyl)benzamide
Show/Hide
|
C34H28F3N7O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0928839
|
N-(2,6-difluorophenyl)-5-[3-(2-{[4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C43H44F3N9O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0928845
|
N-(2,6-difluorophenyl)-2-(methyloxy)-5-{3-[2-({2-(methyloxy)-4-[5-(1-pryrrolidinylmethyl)-1,3,4-oxa-diazol-2-yl]-phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C39H33F2N9O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0928846
|
3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-2-ethylphenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C42H42F2N8O
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0928847
|
N-(2,6-difluorophenyl)-5-[3-(2-{[4-[1'-(2-fluoroethyl)-4,4'-bipiperidin-1-yl]-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C44H45F3N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0929056
|
N-(2,6-difluorophenyl)-3-[3-(2-{[2-(ethyloxy)-4-(4-{1-[2-(methylsulfonyl)ethyl]-4-piperidinyl}-1-piperazinyl)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C44H47F2N9O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0929069
|
5-(3-{2-[(5-chloro-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)-2-(ethyloxy)benzamide
Show/Hide
|
C41H41ClF2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0944891
|
3-[3-(2-{[5-(1,4'-bipiperidin-1'-yl)-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
C41H40F2N8O2
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0944904
|
N-(2,6-difluorophenyl)-2-(methyloxy)-5-(3-{2-[(2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperazinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
|
C39H38F2N8O5S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0946200
|
N-(2,6-difluorophenyl)-5-[3-(2-{[5-methyl-2-(methyloxy)-4-(1-propyl-4-piperidinyl)phenyl]-amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-2-(methyloxy)benzamide
Show/Hide
|
C41H41F2N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0946229
|
N-(2,6-difluorophenyl)-2-isopropoxy-5-{3-[2-({2-methoxy-4-[2-(4-methylpiperazin-1-yl)ethyl]phenyl}amino)pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C41H42F2N8O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0947312
|
N-(2,6-difluorophenyl)-5-{3-[2-({5-fluoro-2-(methyloxy)-4-[2-(4-morpholinyl)ethyl]phenyl}-amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
Show/Hide
|
C38H34F3N7O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0952419
|
N-(2,4-difluorophenyl)-3-[3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}-7-(methyloxy)imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C35H31F2N7O3
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0952675
|
N-(2,6-difluorophenyl)-3-{3-[2-({2-(methyloxy)-4-[2-(4-methyl-1-piperazinyl)ethyl]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
Show/Hide
|
C38H36F2N8O2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0431057
|
1-(3-(5-(4-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(2-phenoxyphenyl)urea
Show/Hide
|
C35H29N5O3
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0195240
|
1-(2-phenylquinolin-7-yl)-3-(3-thiomorpholin-4-ylcyclobutyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C29H28N6S
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0339817
|
3-[3-(azetidin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
|
C28H26N6
|
1
|
| 1 |
IC50 = 147 nM
|
|
|
|
CP0228940
|
3-[3-(dimethylamino)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C27H26N6
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1
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| 1 |
IC50 = 148 nM
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CP0510127
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3-[4-amino-5-(2-phenylquinolin-7-yl)imidazo[5,1-f][1,2,4]triazin-7-yl]-1-methylcyclobutan-1-ol
Show/Hide
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C25H22N6O
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1
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| 1 |
IC50 = 150 nM
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CP0509039
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N-(2,6-difluorophenyl)-3-[3-[2-[4-(2-morpholin-4-ylethyl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C36H31F2N7O2
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1
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| 1 |
IC50 = 174 nM
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CP0338072
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2-N-quinolin-3-yl-4-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazine-2,4-diamine
Show/Hide
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C21H20N6O3
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1
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| 1 |
IC50 = 175 nM
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CP0281203
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2-N-(4-morpholin-4-ylphenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
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C23H22N6O
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1
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| 1 |
IC50 = 177 nM
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CP0261683
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3-[3-[(dimethylamino)methyl]cyclobutyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C26H29N5O
|
1
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| 1 |
IC50 = 191 nM
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CP0085181
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3-[3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(4-phenoxy-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C36H35N7O
|
1
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| 1 |
IC50 = 195 nM
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CP0521482
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(S)-N-(2,6-difluorophenyl)-3-(3-(2-(3-(3-(dimethylamino)-2-hydroxypropoxy)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C35H31F2N7O3
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1
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| 1 |
IC50 = 244 nM
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CP0374509
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N-(2,6-difluorophenyl)-3-[3-[2-[3-(pyrrolidin-1-ylmethyl)anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C35H29F2N7O
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1
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| 1 |
IC50 = 247 nM
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CP0532627
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4-[8-amino-1-(8-fluoro-2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]cyclohexane-1-carboxylic acid
Show/Hide
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C28H24FN5O2
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1
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| 1 |
IC50 = 285 nM
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CP0218529
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7-cyclobutyl-5-(2-phenylquinolin-7-yl)imidazo[1,5-f][1,2,4]triazin-4-amine
Show/Hide
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C24H20N6
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1
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| 1 |
IC50 = 330 nM
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CP0509040
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N-(2,6-difluorophenyl)-3-[3-[2-[4-[3-(dimethylamino)propyl]anilino]pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C35H31F2N7O
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1
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| 1 |
IC50 = 344 nM
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CP0269895
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1-(3-phenylmethoxyphenyl)-3-[3-(piperidin-1-ylmethyl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C29H33N5O
|
1
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| 1 |
IC50 = 346 nM
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CP0216904
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2-N-(3-chloro-4-methoxyphenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
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C20H16ClN5O
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1
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| 1 |
IC50 = 356 nM
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CP0051312
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1-(3-phenylmethoxyphenyl)-3-[3-[(propan-2-ylamino)methyl]cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C27H31N5O
|
1
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| 1 |
IC50 = 376 nM
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CP0505156
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3-{3-[3-(3-Biphenyl-2-yl-ureido)-phenyl]-1H-pyrrolo[2,3-b]pyridin-5-yl}-N,N-dimethyl-benzamide
Show/Hide
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C35H29N5O2
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1
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| 1 |
IC50 = 385 nM
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CP0332955
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3-[4-(azetidin-1-ylmethyl)cyclohexyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C29H33N5O
|
1
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| 1 |
IC50 = 398 nM
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CP0216463
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1-(3-phenylmethoxyphenyl)-3-[3-(pyrrolidin-1-ylmethyl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C28H31N5O
|
1
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| 1 |
IC50 = 401 nM
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CP0505155
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1-(3-(5-(3-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(2-(phenylamino)phenyl)urea
Show/Hide
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C35H30N6O2
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1
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| 1 |
IC50 = 407 nM
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CP0142927
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4-N-naphthalen-2-yl-2-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazine-2,4-diamine
Show/Hide
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C22H21N5O3
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1
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| 1 |
IC50 = 409 nM
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CP0375704
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1-(3-(5-(4-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(2-phenoxyphenyl)urea
Show/Hide
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C37H34N6O3
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1
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| 1 |
IC50 = 415 nM
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CP0222530
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4-N-(2-methylquinolin-3-yl)-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
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C23H23N5O3
|
1
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| 1 |
IC50 = 420 nM
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CP0374513
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N-(2,6-difluorophenyl)-3-[3-[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
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C32H22F2N6O3
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1
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| 1 |
IC50 = 431 nM
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CP0035293
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3-[4-(diethylaminomethyl)cyclohexyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C30H37N5O
|
1
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| 1 |
IC50 = 440 nM
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CP0348689
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4-N-quinoxalin-6-yl-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
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C21H20N6O3
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1
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| 1 |
IC50 = 448 nM
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CP0170857
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4-N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
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C23H27N5O3
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1
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| 1 |
IC50 = 490 nM
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CP0142930
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2-N-(3,4-dimethoxyphenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
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C21H19N5O2
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1
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| 1 |
IC50 = 507 nM
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CP0434321
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N-(2,6-difluorophenyl)-3-[3-[2-(3-fluoroanilino)pyrimidin-4-yl]imidazo[1,2-a]pyridin-2-yl]benzamide
Show/Hide
|
C30H19F3N6O
|
1
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| 1 |
IC50 = 509 nM
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CP0510556
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1-(2-(benzyloxy)phenyl)-3-(3-(5-(3-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)urea
Show/Hide
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C36H31N5O3
|
1
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| 1 |
IC50 = 517 nM
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CP0035296
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3-[4-(aminomethyl)cyclohexyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C26H29N5O
|
1
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| 1 |
IC50 = 534 nM
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CP0035291
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1-(3-phenylmethoxyphenyl)-3-[4-(pyrrolidin-1-ylmethyl)cyclohexyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C30H35N5O
|
1
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| 1 |
IC50 = 547 nM
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CP0145392
|
CHEMBL394154
Show/Hide
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C26H29N5O
|
1
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| 1 |
IC50 = 560 nM
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CP0315637
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1-(3-phenylmethoxyphenyl)-3-[3-(pyrrolidin-1-ylmethyl)cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C28H31N5O
|
1
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| 1 |
IC50 = 621 nM
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CP0315638
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3-[4-(morpholin-4-ylmethyl)cyclohexyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C30H35N5O2
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1
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| 1 |
IC50 = 651 nM
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CP0051314
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3-[3-(morpholin-4-ylmethyl)cyclobutyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C28H31N5O2
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1
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| 1 |
IC50 = 658 nM
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CP0118245
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3-[3-(aminomethyl)cyclobutyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C24H25N5O
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1
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| 1 |
IC50 = 690 nM
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CP0510553
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1-(2-phenoxyphenyl)-3-(3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)urea
Show/Hide
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C32H24N4O2
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1
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| 1 |
IC50 = 693 nM
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CP0261682
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3-[3-[[methyl(piperazin-1-yl)amino]methyl]cyclobutyl]-1-(3-phenylmethoxyphenyl)-1,8a-dihydroimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C29H37N7O
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1
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| 1 |
IC50 = 758 nM
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CP0274496
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4-[8-amino-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclohexane-1-carboxamide
Show/Hide
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C26H27N5O2
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1
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| 1 |
IC50 = 898 nM
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CP0505157
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1-(3-(5-(3-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(3-phenoxyphenyl)urea
Show/Hide
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C35H29N5O3
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1
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| 1 |
IC50 = 961 nM
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CP0471104
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3-methyl-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C22H17N5
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1
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| 1 |
IC50 = 1040 nM
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CP0510555
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3-(3-(3-(3-(2-phenoxyphenyl)ureido)phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)benzoic acid
Show/Hide
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C33H24N4O4
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1
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| 1 |
IC50 = 1041 nM
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CP0206888
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2-N-(3-methoxyphenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
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C20H17N5O
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1
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| 1 |
IC50 = 1044 nM
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CP0474664
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1-[3-[5-[3-(dimethylsulfamoyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-3-(2-phenoxyphenyl)urea
Show/Hide
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C34H29N5O4S
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1
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| 1 |
IC50 = 1116 nM
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CP0051309
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3-cyclobutyl-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H22N4O
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1
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| 1 |
IC50 = 1160 nM
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CP0510554
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1-[3-[5-(furan-3-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-3-(2-phenoxyphenyl)urea
Show/Hide
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C30H22N4O3
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1
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| 1 |
IC50 = 1264 nM
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CP0091958
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1-(3-(2,6-difluorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H20F2N4O
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1
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| 1 |
IC50 = 1590 nM
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CP0035289
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3-[8-amino-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutane-1-carboxamide
Show/Hide
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C24H23N5O2
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1
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| 1 |
IC50 = 1710 nM
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CP0091954
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4-[8-amino-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]-N-methylcyclohexane-1-carboxamide
Show/Hide
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C27H29N5O2
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1
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| 1 |
IC50 = 1720 nM
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CP0261681
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1-(3-(2-fluorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H21FN4O
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1
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| 1 |
IC50 = 2060 nM
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CP0035286
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3-[8-amino-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclobutane-1-carboxamide
Show/Hide
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C24H23N5O2
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1
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| 1 |
IC50 = 2080 nM
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CP0302311
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1-(3-(2-chloro-6-fluorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H20ClFN4O
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1
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| 1 |
IC50 = 2670 nM
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CP0407643
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1-(3-(5-(3-(dimethylcarbamoyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(4-phenoxyphenyl)urea
Show/Hide
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C35H29N5O3
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1
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| 1 |
IC50 = 3071 nM
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CP0315682
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1-(3-(3-fluorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H21FN4O
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1
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| 1 |
IC50 = 3290 nM
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CP0302480
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2-N-(3-chlorophenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
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C19H14ClN5
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1
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| 1 |
IC50 = 3377 nM
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CP0407644
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3-(4-(3-(3-(3-(2-phenoxyphenyl)ureido)phenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)propanoic acid
Show/Hide
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C35H28N4O4
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1
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| 1 |
IC50 = 3623 nM
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CP0338073
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4-N-(3H-benzimidazol-5-yl)-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
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C20H20N6O3
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1
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| 1 |
IC50 = 4221 nM
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CP0291440
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4-N-(1H-indazol-5-yl)-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
Show/Hide
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C20H20N6O3
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1
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| 1 |
IC50 = 5121 nM
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CP0315678
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1-(3-(2,3-difluorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H20F2N4O
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1
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| 1 |
IC50 = 5690 nM
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CP0375030
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2,6-difluoro-N-(3-(3-(2-(3-(pyrrolidin-1-ylmethyl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)phenyl)benzamide
Show/Hide
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C35H29F2N7O
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1
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| 1 |
IC50 = 5930 nM
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CP0514454
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1-(3-(5-(1H-pyrrol-2-yl)-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)-3-(2-phenoxyphenyl)urea
Show/Hide
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C30H23N5O2
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1
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| 1 |
IC50 = 7463 nM
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CP0261684
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4-[8-amino-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-3-yl]cyclohexane-1-carboxamide
Show/Hide
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C26H27N5O2
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1
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| 1 |
IC50 = 8570 nM
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CP0145394
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1-(3-(2,5-difluorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H20F2N4O
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1
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| 1 |
IC50 = 9760 nM
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CP0315681
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1-(3-(4-chlorobenzyloxy)phenyl)-3-cyclobutylimidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C23H21ClN4O
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1
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| 1 |
IC50 > 10000 nM
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CP0310316
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3-cyclobutyl-1-(quinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine
Show/Hide
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C19H17N5
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1
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| 1 |
IC50 > 10000 nM
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CP0457548
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3-cyclobutyl-1-(2-phenylquinolin-7-yl)-7H-imidazo[1,5-a]pyrazin-8-one
Show/Hide
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C25H20N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0142931
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2-N-(4-methoxyphenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
Show/Hide
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C20H17N5O
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1
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| 1 |
IC50 = 17383 nM
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CP0431058
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1-[3-[5-[4-(dimethylsulfamoyl)phenyl]-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-3-(2-phenoxyphenyl)urea
Show/Hide
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C34H29N5O4S
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1
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| 1 |
IC50 = 20793 nM
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CP0514748
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3-(3-(2-aminopyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C24H16F2N6O
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1
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| 1 |
IC50 > 30000 nM
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CP0848469
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3-{3-[2-({4-(1,4'-bipiperidin-1'-yl)-2-[(2-methylpropyl)oxy]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C44H46F2N8O2
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1
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| 1 |
IC50 > 500 nM
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CP0857319
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N-(2,6-difluorophenyl)-5-{3-[2-({2-(ethyloxy)-4-[2-(4-methyl-1-piperazinyl)ethyl]-phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
Show/Hide
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C38H36F2N8O3
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1
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| 1 |
IC50 > 500 nM
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CP0895724
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N-(2,6-difluorophenyl)-5-(3-(2-(3-(2-(dimethylamino)ethoxy)phenylamino)pyrimidin-4-yl)-7-methylimidazo[1,2-a]pyridin-2-yl)-2-methoxybenzamide
Show/Hide
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C36H33F2N7O3
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1
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| 1 |
IC50 > 500 nM
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CP0921733
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3-[3-(2-{[4-(1,4'-bipiperidin-1'-yl)-3-methyl-2-(methyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]-N-(2,6-difluorophenyl)benzamide
Show/Hide
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C42H42F2N8O2
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1
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| 1 |
IC50 > 500 nM
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CP0944890
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N-(2,6-difluorophenyl)-3-(3-{2-[(3-{[2-(dimethylamino)ethyl]oxy}phenyl)amino]-4-pyrimidinyl}-7-methylimidazo[1,2-a]pyridin-2-yl)benzamide
Show/Hide
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C35H31F2N7O2
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1
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| 1 |
IC50 > 500 nM
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