Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(3-phenylmethoxyphenyl)-3-[3-[(propan-2-ylamino)methyl]cyclobutyl]imidazo[1,5-a]pyrazin-8-amine
    Show/Hide
Canonical SMILES
CC(C)NC[C@H]1C[C@H](C1)c1nc(-c2cccc(OCc3ccccc3)c2)c2c(N)nccn12
    Show/Hide
Compound Formula C27H31N5O
Compound Structure
Protein Name
 Protein Info 
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 376 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 220 nM