Brief Information of the Compound and Protein
Compound Name
3-[4-(aminomethyl)cyclohexyl]-1-(3-phenylmethoxyphenyl)imidazo[1,5-a]pyrazin-8-amine
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Canonical SMILES
NC[C@H]1CC[C@@H](CC1)c1nc(-c2cccc(OCc3ccccc3)c2)c2c(N)nccn12
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Compound Formula C26H29N5O
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 534 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 119 nM