Brief Information of the Compound and Protein
Compound Name
2-N-(3-methoxy-4-morpholin-4-ylphenyl)-4-N-quinolin-3-ylpyrimidine-2,4-diamine
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PubChem ID
CID: 10202829
SID: 15200961
Canonical SMILES
COc1cc(Nc2nccc(Nc3cnc4ccccc4c3)n2)ccc1N1CCOCC1
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Compound Formula C24H24N6O2
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 8.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.4 nM