General Information of the Compound
| Compound ID |
CP0856490
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
3-{3-[2-({4-(1,4'-bipiperidin-1'-yl)-2-[(1-methylethyl)oxy]phenyl}amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-N-(2,6-difluorophenyl)benzamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C43H44F2N8O2
|
||||||||||||||||||
| Molecular Weight |
742.875
|
||||||||||||||||||
| Canonical SMILES |
CC(C)Oc1cc(N2CCC(N3CCCCC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C43H44F2N8O2/c1-28(2)55-37-27-32(52-24-18-31(19-25-52)51-21-5-3-6-22-51)15-16-35(37)47-43-46-20-17-36(48-43)41-39(49-38-14-4-7-23-53(38)41)29-10-8-11-30(26-29)42(54)50-40-33(44)12-9-13-34(40)45/h4,7-17,20,23,26-28,31H,3,5-6,18-19,21-22,24-25H2,1-2H3,(H,50,54)(H,46,47,48)
Show/Hide
|
||||||||||||||||||
| InChIKey |
QSNLBMCGRQUEPH-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor