Brief Information of the Compound and Protein
Compound Name
1-(2-phenoxyphenyl)-3-(3-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl)urea
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PubChem ID
CID: 45270370
Canonical SMILES
O=C(Nc1cccc(c1)-c1c[nH]c2ncc(cc12)-c1ccccc1)Nc1ccccc1Oc1ccccc1
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Compound Formula C32H24N4O2
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 693 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 127 nM
   TI
   LI
   LO
   TS