Brief Information of the Compound and Protein
Compound Name
4-N-isoquinolin-3-yl-2-N-(3,4,5-trimethoxyphenyl)pyrimidine-2,4-diamine
    Show/Hide
PubChem ID
CID: 10222816
SID: 15223794
Canonical SMILES
COc1cc(Nc2nccc(Nc3cc4ccccc4cn3)n2)cc(OC)c1OC
    Show/Hide
Compound Formula C22H21N5O3
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000035 NIH 3T3 Mus musculus (Mouse)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.2 nM