General Information of the Compound
| Compound ID |
CP0848538
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| Compound Name |
N-(2,6-difluorophenyl)-3-[3-(2-{[2-methyl-4-(4-piperidinyloxy)phenyl]amino}-4-pyrimidinyl)imidazo[1,2-a]pyridin-2-yl]benzamide
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| Structure |
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| Formula |
C36H31F2N7O2
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| Molecular Weight |
631.687
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| Canonical SMILES |
Cc1cc(OC2CCNCC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1
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| InChI |
InChI=1S/C36H31F2N7O2/c1-22-20-26(47-25-13-16-39-17-14-25)11-12-29(22)41-36-40-18-15-30(42-36)34-32(43-31-10-2-3-19-45(31)34)23-6-4-7-24(21-23)35(46)44-33-27(37)8-5-9-28(33)38/h2-12,15,18-21,25,39H,13-14,16-17H2,1H3,(H,44,46)(H,40,41,42)
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| InChIKey |
MQIAKZLWCNEYGB-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor