General Information of the Compound
| Compound ID |
CP0870269
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| Compound Name |
N-(2,6-difluorophenyl)-3-(3-(2-(3-(1-methyl-1H-pyrazol-4-yl)phenylamino)pyrimidin-4-yl)imidazo[1,2-a]pyridin-2-yl)benzamide
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| Structure |
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| Formula |
C34H24F2N8O
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| Molecular Weight |
598.617
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| Canonical SMILES |
Cn1cc(-c2cccc(Nc3nccc(-c4c(-c5cccc(C(=O)Nc6c(F)cccc6F)c5)nc5ccccn45)n3)c2)cn1
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| InChI |
InChI=1S/C34H24F2N8O/c1-43-20-24(19-38-43)21-7-5-10-25(18-21)39-34-37-15-14-28(40-34)32-30(41-29-13-2-3-16-44(29)32)22-8-4-9-23(17-22)33(45)42-31-26(35)11-6-12-27(31)36/h2-20H,1H3,(H,42,45)(H,37,39,40)
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| InChIKey |
JGMJCQJURLCLJC-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor