General Information of the Compound
| Compound ID |
CP0866987
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| Compound Name |
N-(2,6-difluorophenyl)-3-{3-[2-({5-fluoro-2-(methyloxy)-4-[2-(1-piperidinyl)ethyl]phenyl}-amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}benzamide
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| Structure |
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| Formula |
C38H34F3N7O2
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| Molecular Weight |
677.731
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| Canonical SMILES |
COc1cc(CCN2CCCCC2)c(F)cc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1
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| InChI |
InChI=1S/C38H34F3N7O2/c1-50-32-22-24(15-20-47-17-4-2-5-18-47)29(41)23-31(32)44-38-42-16-14-30(43-38)36-34(45-33-13-3-6-19-48(33)36)25-9-7-10-26(21-25)37(49)46-35-27(39)11-8-12-28(35)40/h3,6-14,16,19,21-23H,2,4-5,15,17-18,20H2,1H3,(H,46,49)(H,42,43,44)
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| InChIKey |
LZLZAMJAYXYMOK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor