General Information of the Compound
| Compound ID |
CP0895688
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| Compound Name |
N-(2,6-difluorophenyl)-3-(3-{2-[(2-(ethyloxy)-4-{4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)benzamide
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| Structure |
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| Formula |
C43H44F3N9O2
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| Molecular Weight |
775.88
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| Canonical SMILES |
CCOc1cc(N2CCC(N3CCN(CCF)CC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1
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| InChI |
InChI=1S/C43H44F3N9O2/c1-2-57-37-28-32(53-20-15-31(16-21-53)54-25-23-52(22-17-44)24-26-54)12-13-35(37)48-43-47-18-14-36(49-43)41-39(50-38-11-3-4-19-55(38)41)29-7-5-8-30(27-29)42(56)51-40-33(45)9-6-10-34(40)46/h3-14,18-19,27-28,31H,2,15-17,20-26H2,1H3,(H,51,56)(H,47,48,49)
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| InChIKey |
IEXAEHAHMUVCRY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor