General Information of the Compound
| Compound ID |
CP0921734
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| Compound Name |
N-(2,6-difluorophenyl)-5-{3-[2-({2-(ethyloxy)-4-[4-(1-methylethyl)-1-piperazinyl]phenyl}-amino)-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl}-2-(methyloxy)benzamide
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| Structure |
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| Formula |
C40H40F2N8O3
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| Molecular Weight |
718.809
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| Canonical SMILES |
CCOc1cc(N2CCN(C(C)C)CC2)ccc1Nc1nccc(-c2c(-c3ccc(OC)c(C(=O)Nc4c(F)cccc4F)c3)nc3ccccn23)n1
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| InChI |
InChI=1S/C40H40F2N8O3/c1-5-53-34-24-27(49-21-19-48(20-22-49)25(2)3)13-14-31(34)44-40-43-17-16-32(45-40)38-36(46-35-11-6-7-18-50(35)38)26-12-15-33(52-4)28(23-26)39(51)47-37-29(41)9-8-10-30(37)42/h6-18,23-25H,5,19-22H2,1-4H3,(H,47,51)(H,43,44,45)
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| InChIKey |
GGCSJXJBJIBXQQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01101, Insulin receptor
Protein ID: PT01104, Insulin-like growth factor 1 receptor